Page 28 - Peer Reviewed Laparoscopic Jornal

Chukwuemeka Chukwunwendu Osuagwu

Postoperative wound infection SPLC: CLC 3:4 for seroma/ hematoma None Incisional hernia at 3 months in SPLC None None No difference — —- Wound infection higher in SILS (p = 0.047) but hernia were equal in both arms

Table 1: Randomized controlled trials comparing single-port laparoscopic cholecystectomy with conventional laparoscopic cholecystectomy
Conversion 2 SPLC converted 1 LC converted to SPC due to adhesions None One SPLC to four-port LC No conversion None —- —- —- Two SPLC were converted Conversion to CLC in one patient

Difficult exposure and bile duct injuries None None None D + (0.004) None —- CBD leakage in one CLC and two SPLC had postoperative bile leakage —- None

Cosmesis Better cosmetic outcome and body image scar scale (p < 0.001) Better cosmesis with SPLC (p = 0.05) SPLC had better body image cosmesis from 1 week, p = 0.0002- 0.0004) at 3 months Better cosmesis (p = 0.025) SPLC has better cosmesis No difference — Cosmesis better in SPLC but it is not statistically significant SPLC better satisfaction (0.012) Cosmesis better for SPLC (p = 0.002)

Postoperative pain SPLC; reduced postoperative pain (p < 0.001) No difference in postoperative pain No difference in pain CLC less painful first day postoperative pain p = 0.04 SPLC more painful on day 7 compared to LC No difference Two blinded independent less pain in SPLC SPLC lower pain at umbilical (0.002 at rest and during movement) and other sites (0.004) SPLC less post- operative pain and mean pain index lower (p =

Operation time Similar Operation time was longer in SPLC (p < 0.04) Longer in SPLC (p < 0.003) Double blinded longer operation time in SPLC (0.001) Longer for SPLC Significantly longer operation time in SPLC (p < 0.05) Operation time is longer in SPLC Similar operation time Operation time longer in SPLC (0.03) Blinded multicenter RCT (10 centers) Operation time Longer in SPLC (p < 0.00001)

Number of patients in single port laparoscopic cholecystectomy controls 75 25 33 20 27 22 20 26 30 80 SPLC: Single port laparoscopic cholecystectomy; CLC: Conventional laparoscopic cholecystectomy; RCT: Randomized controlled trials

Number of patients in single port laparoscopic cholecystectomy study arm 75 25 50 20 24 21 20 24 28 117

Authors Bucher P, Pugin F, Buchs N, Ostermann S et al 23 Aprea G, Bottazz E, Guida F, Masone S et al 29 Marks J, Tacchino R, Roberts K, Onders R et al 25 Lirici, M, Califano, A, Angelini, P, Corcione F 16 Lai E, Yang G, Tang C, Yih P, Chan O, Li M 30 Ma J, Maria S, Georg O, Hammill C et al 27 Tsimoyiannis EC, Tsimogiannis KE, Pappas-Gogos G et al 18 Chang S, Wang Y, Shen L, Iyer S, Shaik A, Lomanto D et al 24 Zheng M et

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