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          10.5005/jp-journals-10033-1189
           SYSTEMATIC REVIEW     A Review of Randomized Controlled Trials comparing Single Port Laparoscopic Cholecystectomy
          A Review of Randomized Controlled Trials comparing

          Single Port Laparoscopic Cholecystectomy with

          Conventional Laparoscopic Cholecystectomy


          Chukwuemeka Chukwunwendu Osuagwu


                                                                            9
          ABSTRACT                                            physical activity  as well as comparative levels of patient
          Aim:  To determine the safety and benefits of single port  safety. During conventional, traditional, four-port
          laparoscopic cholecystectomy.                       laparoscopic cholecystectomy complementary procedures,
          Materials and methods: A search for randomized controlled  such as laparoscopic intraoperative cholangiography using
                                                                                      10
          trials comparing single port laparoscopic cholecystectomy with  contrast may be performed  to define the extrahepatic
          conventional laparoscopic cholecystectomy was conducted  biliary anatomy and determine the presence of common bile
          using Google scholar, HighPress and SCOPUS.
                                                              duct stone. Some authors have also performed transcystic
          Results: Single port laparoscopic cholecystectomy has a longer  duct balloon dilatation of sphincter of Oddi during
          operating time, with equivocal postoperative pain, and offers
          better cosmetic result with low morbidity.          conventional laparoscopic cholecystectomy which is
                                                              effective in flushing common bile duct stones into the
          Conclusion: Single port laparoscopic cholecystectomy is at
          least as safe as conventional laparoscopic cholecystectomy in  duodenum in 85% of cases. 11
          carefully selected patients.                           In 1997, Navarra performed the first single incision
                                                                                        12
          Keywords:  Single incision laparoscopic cholecystectomy,  laparoscopic cholecystectomy.  Single incision laparos-
          Conventional laparoscopy, Randomized controlled trial.  copic cholecystectomy also goes by other terminologies,
          How to cite this article:  Osuagwu CC. A Review of  such as transumbilical laparoscopic cholecystectomy, 13
          Randomized Controlled Trials comparing Single Port  single port laparoscopic cholecystectomy,  natural orifice
                                                                                                 14
          Laparoscopic Cholecystectomy with Conventional Laparoscopic                     15
          Cholecystectomy. World J Laparosc Surg 2013;6(2):93-97.  transumbilical surgery (NOTUS)  cholecystectomy and
                                                                                                          16
                                                              laparoendoscopic single site (LESS) cholecystectomy.  The
          Source of support: Nil
                                                              popularity of single incision laparoscopic surgery is driven
          Conflict of interest: None declared
                                                                                           17
                                                              by reports of improved cosmesis,  further reduction in
          INTRODUCTION                                        postoperative pain alongside comparative safety. 18
                                                              However, there are difficulties with swording of instruments
          Gallstone disease is a common surgical condition. Everhart  and loss of triangulation  as well as increased operating
                                                                                   19
          et al in a national survey in the United States found that  time, and port site hernia, and increased risk of conversion.
          6.3 million men and 14.2 million women who were within  The safety of single port laparoscopic cholecystectomy
          the age range of 20 to 74 years were afflicted with  should be determined compared with the standard of
          gallbladder disease. Gallstone disease is a least twice as  care as recent reports suggest that advanced procedures,
                                     1
          common in females as in males.  In Europe, the prevalence  such as laparoscopic cholangiography is being undertaken
          was found to vary from 5.9% in Italy to 21.9% in Norway. 2  during single port laparoscopic cholecystectomy with
          The incidence rate in Europe is about 0.63 to 0.93/100  some success. 20,21  Therefore, it is necessary to review
                     3,4
          persons/year  which may reflect the increasing demand  randomized control trials that compared the single port
          for cholecystectomy. In Taiwan, a lower prevalence of  laparoscopic cholecystectomy with the four-port laparos-
          gallstone disease was noted 4.6% in men and 5.4% in  copic cholecystectomy.
          women; however, there was no difference in sex prevalence. 5
          In Africa, a hospital prevalence of 747 cases in 4 years with  AIM
          a male to female ratio of 1:5 was also reported. 6  To compare safety of single incision laparoscopic chole-
             Cholecystectomy is the proven treatment for      cystectomy with conventional laparoscopic cholecystectomy
                                    6
          symptomatic gallstone disease.  Open cholecystectomy is  with emphasis on the operating time, postoperative pain,
          the mainstay of surgical treatment of gallbladder disease;  and cosmesis (Table 1), and bile duct injuries as well as
          however, it has evolved in terms of the access to the  conversion rate.
          gallbladder. Muhe in 1985 introduced laparoscopic
                         7
          cholecystectomy,  which subsequently, became the gold  MATERIALS AND METHODS
                       8
          standard of care  because it offered better cosmetic outcome,  A search of published randomized controlled trails
          reduced postoperative pain with early return to normal  comparing single port laparoscopic cholecystectomy with
          World Journal of Laparoscopic Surgery, May-August 2013;6(2):93-97                                 93
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