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Clinical Profile and Laparoscopic Management of Hiatus Hernia
               A recent open-label randomized controlled trial comparing   references
            PPI treatment with TF found that TF was superior to PPI in
            controlling problematic GERD symptoms, with 54% of patients     1.  Smith RE, Shahjehan RD. Hiatal Hernia. [Updated 2022 Jan 14]. In:
                                                                    StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing;
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            reaching normalization of intraesophageal pH after TF.  Our   2022 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/
            routine follow-up proved 67% success rates for patients treated   NBK562200/.
            surgically.                                          2.  Kellerman R, Kintanar T. Gastroesophageal reflux disease. Primary
               A retrospective analysis of 50 surgical cases of GERD in   Care 2017;44(4):561–573. DOI: 10.1016/j.pop.2017.07.001.
            Japan revealed that just four patients (8%) had postoperative     3.  Yadlapati R, Gyawali CP, Pandolfino JE, and CGIT GERD Consensus
            problems, which is very comparable to our study (8.3%). They also   Conference Participants. AGA clinical practice update on the
            determined in their study utilizing the frequency scale for the   personalized approach to the evaluation and management of GERD:
            symptoms of GERD—that there was a considerable improvement   Expert review. Clin Gastroenterol Hepatol 2022;20(5):984–994.e1.
            in postoperative symptoms, which accounted for a 90% overall   DOI: 10.1016/j.cgh.2022.01.025.
            efficacy rate. 9                                     4.  Hunter JG, Kahrilas PJ, Bell RCW. Efficacy of transoral fundoplication
               Dallemagne et al. summarized that laparoscopic fundoplication   vs omeprazole for treatment of regurgitation in a randomized
                                                                    controlled trial. Gastroenterology 2015;148(2):324–333.e5. DOI:
            can be used as a “gold standard” treatment of GERD among   10.1053/j.gastro.2014.10.009.
                                                    10
            appropriately investigated and selected individuals.  Our study     5.  Vakil N, van Zanten SV, Kahrilas P, et al. Die Montreal-Definition und -
            is limited by a small sample size and the population is limited to   Klassifikation der gastroösophagealen Refluxkrankheit: Ein globales
            one tertiary care center. However, the results obtained contrast   evidenzbasiertes Konsensus-Papier [The Montreal definition and
            the reasons for outcomes observed in surgical as well as medical   classification of gastroesophageal reflux disease: A global, evidence-
            management of GERD.                                     based consensus paper]. Z Gastroenterol 2007;45(11):1125–1140.
                                                                    DOI: 10.1055/s-2007-963633.
                                                                 6.  Galindo G, Vassalle J, Marcus SN, et al. Multimodality evaluation
            conclusIon
                                                                    of patients with gastroesophageal reflux disease symptoms who
            Laparoscopic TF is fast being adopted as the surgical gold   have failed empiric proton pump inhibitor therapy. Dis Esophagus
            standard for treatment of GERD after appropriate trial of medical   2013;26(5):443–450. DOI: 10.1111/j.1442-2050.2012.01381.x.
            management, and our study reaffirms this concept among the      7.  Sigterman KE, van Pinxteren B, Bonis PA., et al. Short-term treatment
            population presenting in an Indian tertiary care hospital. This study   with proton pump inhibitors, H2-receptor antagonists and
            sheds light on the high efficacy of PPI regimens and the utility   prokinetics for gastro-oesophageal reflux disease-like symptoms
            of laparoscopic fundoplication in necessitated patients toward   and endoscopy negative reflux disease. Cochrane Database Syst Rev
            providing adequate relief from GERD symptoms.           2013(5):CD002095. DOI: 10.1002/14651858.CD002095.pub5.
                                                                 8.  Zerbib F, Bredenoord AJ, Fass R, et al. ESNM/ANMS consensus paper:
            Clinical Significance                                   Diagnosis and management of refractory gastro-esophageal reflux
                                                                    disease. Neurogastroenterology Motil 2021;33(4):e14075. DOI: 10.1111/
            The study results would improve treatment outcomes in patients   nmo.14075.
            with hiatus hernia.                                  9.  Seki Y, Watanabe T, Umezawa A, et  al. Laparoscopic Nissen
                                                                    fundoplication for gastroesophageal reflux disease: A retrospective
            orcId                                                   study of 50 consecutive cases. Gastroenterol Pancreatol Liver Disord
                                                                    2015;2(4):1–5. DOI: 10.15226/2374-815X/2/4/00143.
            Akanksha Talwar   https://orcid.org/0000-0002-1846-3244    10.  Dallemagne B, Weerts J, Markiewicz S, et al. Clinical results of
            Pavan Madhukar Bhat   https://orcid.org/0000-0001-6399-9104  laparoscopic fundoplication at ten years after surgery. Surgical
            Sunil Krishna   https://orcid.org/0000-0002-8740-3616   Endosc 2006;20(1):159–165. DOI: 10.1007/s00464-005-0174-x.
































             24   World Journal of Laparoscopic Surgery, Volume 16 Issue 1 (January–April 2023)
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