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ORIGINAL ARTICLE
            Barbed vs Polyglactin 910: A Comparative Study of the

            Efficacy in Laparoscopic Vaginal Cuff Closure


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            Prathap Talwar , Lakshmi Velayudam , Hema PL Kukreja , Soumya R Patil 4
             AbstrAct
             Context: Total laparoscopic hysterectomy (TLH) is a popular mode of hysterectomy in the recent times. One of the principal steps is vaginal cuff
             closure, with many variations in surgical technique and materials. Intracorporeal suturing and knot-tying are crucial steps and are considered
             to be the most technically difficult skills. To overcome these challenges and learning curve, various measures have been emerging. One among
             them is the introduction of barbed suture, a new class of suture material.
             Aim: To evaluate whether the use of barbed suture for vaginal cuff closure during TLH reduced the surgical difficulty and suturing time when
             compared to polyglactin 910 suture.
             Materials and methods: This randomized comparative study included 100 patients divided into two groups of 50 each, who underwent TLH
             with vault closure using either barbed sutures or polyglactin 910. Demographic details, indication for surgery, intraoperative complications,
             mean suturing time, surgeon difficulty, and average hospital stay were compared between the two groups.
             Statistical analysis: Student t test for continuous variables and Fischer exact test for categorical variables. p values ≤ 0.05 were considered
             significant.
             Results: Use of barbed suture has significantly reduced the suturing time for vaginal vault closure (5.39 vs 6.9 minutes, p value < 0.0001) as well
             as the technical difficulty in laparoscopic suturing (p value < 0.0001) when compared to that with polyglactin 910.
             Conclusion: The introduction of barbed sutures for vault closure during TLH not just reduces the suturing time but is also technically less
             demanding, making it a potential asset in laparoscopic hysterectomies.
             Keywords: Barbed suture, Polyglactin 910, Total laparoscopic hysterectomy, Vault closure.
             World Journal of Laparoscopic Surgery (2020): 10.5005/jp-journals-10033-1415


            IntroductIon                                       1–4 Department of Obstetrics and Gynaecology, JSS Medical College

            Hysterectomy is the most frequently performed gynecological   and Research Institute, Mysuru, Karnataka, India
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            surgery in the world.  This procedure can be performed through   Corresponding  Author: Soumya R Patil, Department of Obstetrics
            abdominal, vaginal, or laparoscopic access. Besides, robotic-assisted   and Gynaecology, JSS Medical College and Research Institute, Mysuru,
            laparoscopy and single-port hysterectomy have been developed   Karnataka, India, Phone: +91 9739667595, e-mail: soumyarpatil999@
            in the recent years.                               gmail.com
               Harry Reich performed the first laparoscopic hysterectomy   How to cite this article: Talwar P,  Velayudam L, Kukreja HPL,  et al.
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            in 1988 in Pennsylvania.  Since then, laparoscopic hysterectomy   Barbed  vs  Polyglactin  910:  A  Comparative  Study  of  the  Efficacy  in
            has proven to be a safer choice than traditional surgery for benign   Laparoscopic  Vaginal Cuff Closure.  World J Lap Surg 2020;13(3):
            gynecological conditions. The progress in the field of minimally   113–116.

            invasive surgery has transformed laparoscopic hysterectomy into   Source of support: Nil
            most popular mode of hysterectomy in the recent times due to its   Conflict of interest: None
            cosmetic superiority, shorter hospital stay, quicker resumption of
            day-to-day activities, and reduced morbidity. 3    vault dehiscence, the knots performed laparoscopically should be
               In total laparoscopic hysterectomy, there are significant   as safe as the traditional approach.
            variations in the vaginal cuff closure with respect to mode of   However, intracorporeal suturing and knot tying are considered
            suturing, suturing technique, and suture materials used. Vaginal   to be the most technically difficult skills. The fundamentals of a
            vault closure is done by intracorporeal sutures or transvaginal   perfect knot-tying demands easiness, rapid execution, tight knot,
            sutures, by continuous or interrupted sutures, and in single or   easily reproducible steps, and, also very importantly, the type
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            double layers using knotted or unknotted stitches.  Although   of suture material used. Performing this laparoscopically is most
            widely used, conventional sutures may become loose or entangled,   challenging and necessitates adequate skill and experience.
            requiring constant traction by an assistant or the operating surgeon,   Therefore, it becomes essential to seek a more convenient
            all of which may cause instrument collision and tissue tearing   technique and safer surgical material to overcome the learning
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            leading to prolongation of suturing.  Laparoscopic intracorporeal   curve required for intracorporeal suturing. One such has been the
            closure has several advantages, such as longer postoperative   introduction of barbed sutures, which maintain the tensile strength
            vaginal length, minimizing granulation tissue as the vault margins   evenly along the entire length of the wound and reapproximates
            are not everted into the vagina and provide an excellent vault   tissue without the use of surgical knot. The favorable results
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            support by incorporating the pericervical ring.  To prevent vaginal   obtained in several studies suggest that the suture material has the

            © The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.
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