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Elective Laparoscopic Left Colectomy for Diverticular Disease: A Monocentric Study on 205 Consecutive Patients

                                                 TABLE 1:  Indications for surgery

                                                                     Nr. patients              %
            Non-complicated acute                                    164                       80
            diverticulitis *
            Complicated diverticulitis
            (acute or chronic)                                       37                        18.05

                                    Abscess (10)
                                    Peritonitis/Perforation (4)
                                    Fistula (6)
                                    Stenosis (17)
            Bleeding diverticular disease *                          4                         1.95

                            Total                                    205                      100


            for descending the proximal colonic stump after an adequate  obese patients (BMI > 30) representing 11.7% of the population
            resection); (2) systematic identification of the left ureter with  studied.
            placement of a provisory landmark; (3) medial mesocolic  Antecedents of past abdominal surgery were noted in the
            dissection for ligature of the left colonic vessels as appropriate;  majority (60%) of the patients. The most frequent previous scars
            (4) distal dissection and division of the rectum sufficiently below  founded were those of appendectomy (n = 28), diverse
            the rectosigmoid junction; (5) liberation of the descending colon  laparotomies (n = 31), both appendectomy and laparotomy
            by a lateral approach; (6) exteriorization and transection of the   (n = 30) and Pfannestiel (n =13). Comorbidities included diabetes
            left colon through a small LLQ incision and insertion of the  in 12 (5.8%) and steroid therapy in 6 (2.9%) of  subjects with
            stapler anvil; (7) closure of the small incision and completion of  79% being ASA classification 1 or 2, 13.1% of ASA 3 and only
            the anastomosis intra-abdominally after restablishing the  0.5% of ASA 4.
            pneumoperitonium.                                     The median time from the onset of symptoms was 15 (1-240)
                                                               months, with a median of 2 (0-12) previous acute attacks and a
            Statistical Analysis                               median of 1 (0-4) previous hospitalizations for acute attacks.
                                                               The most frequent surgical indication was for non-complicated
            A statistical logistic univariate and multivariate model was built  acute diverticulitis (80%), acute or chronic complicated diverti-
            trying to identify possible risk factors for adverse outcomes in  culitis (18.05%) and bleeding diverticular disease (1.9.5%)
            the population studied. Multiple different variables were tested  (Table 1). The complicated diverticulitis consisted of stenosis
            for its effects over the rates of conversion, complications, re-  (n = 17), abscess (n = 10), fistula (n = 6) and peritonitis/perforation
            operation and postoperative functional disorder. The Fisher’s  (n = 4).
            exact test was used for qualitative variables analysis, Student  Preoperative studies used were contrast enema (95.6%),
            t-test for quantitative variables analysis and Mann and Whitney  colonoscopy (84.8%), ultrasonography (77%) and CT scan
            test for non parametric variables analysis. To build logistic  (72.7%).
            multivariate analysis, only variables which were statistically  Causes of conversion, risk factors and complications of the
            significant in univariate model (p < 0.1) were kept. Results for  surgery is presented in Table 2 to 9.
            logistic multivariate model are presented as odds-ratio. All
            statistical analysis were done using Stata 10.0 software (Stata  Operative
            Corp LP, College Station, TX).                     Associated lesions were presented 40 (19.51%) of patients.
                                                               Those consisted of gallbladder stones (n = 15); benign colonic
            RESULTS                                            neoplasms (n = 12); hernias of the abdominal wall  (n = 5);
            Preoperative                                       adnexal masses (n = 4); colon cancer (n= 1); Meckel’s
                                                               diverticulum (n = 1); renal cyst (n = 1) and a cyst of the biliary
            Patients were 107 (52.2%) women and 98 (47.8%) men with a  tract (n = 1). Intraoperative adhesions were noted in 36  (17.56%)
            median age of 60 (30-90) years. There were 46 (22.4%) subjects  cases.
                                                        2
            aged < 50 years.  The mean BMI was 25.3 (+ 3.5) kg/m  with  There were 10 intraoperative complications (Table 10).



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