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                             Laparoscopic Appendectomy: Is it the Gold Standard Approach for Management of Acute Appendicitis?
             Exclusion criteria: Patients­unfit­for­general­anesthesia,­ ReSuLTS
          children below 10 years, pregnancy (second and third   In­this­study,­all­patients­were­planned­to­go­for­LA.­
          trimester), chronic medical diseases, such as cirrhosis,   The demographic data (age, gender), comorbidities and
          coagulation disorders and previous laparotomy for bowel   clinical presentation of the patients were included in
          obstruction.                                        Table 2.
             Preoperative workup in the form of complete history      In the present study, out of total 573 patients, appen­
          taking, complete clinical examination, laboratory (com­  diceal pathology was found in 504 patients (87.9%). No patho­
          plete blood picture and urine analysis), and radiological   logy was observed in the appendix after histopathological
          examination includes abdominal ultrasonography for   examination in 38 (6.7%) patients. Non appendiceal patho­
          all patients and CT abdomen was done for some patients   logy was found in 31 patients (5.4%). Conversion to open
          with­unproved­diagnosis.­Modified­Alvarado­scoring­  procedure was done in 11 (1.9%) patients. The causes of
          system (Table 1) was used as a guide in diagnosing all   conversion­were:­right­hemicolectomy­in­five­patients,­
                 7
          patients.  Written fully informed consent was given by   small intestinal resection (minilaparotomy for Mickle’s
          all patients.                                       diverticulitis in four patients and appendicular mass
             Technique of the procedure: A 10 mm trocar was placed   in two patients (in one case the appendix was ampu­
          just above the umbilicus for the camera and 2 additional   tated from the cecum during dissection and the stump
          working 5 mm trocars were inserted, one suprapubic   cannot­be­identified­and­the­other­case­due­to­suspected­
          and the site of the other trocar depends on the patho­   cecal injury but on open procedure it was negative). The
          logy­detected­and­abdominal­configuration­of­the­patient­  mean operative time in this study was 42 ± 17.54 minutes
          mostly left iliac fossa (sometimes this trocar was replaced   (Table 3).
          by 10 mm depending on the size of the appendix as it is      Wound infection had occurred in 16 patients (2.8%).
          the extraction port). The patient was placed in a Tren­  One patient developed postoperative intra­abdominal
          delenburg position, with right side slightly up (a slight   abscess (IAA), she was from the start appendicular
          rotation to the left). The abdominal cavity was thoroughly   abscess and the drain was removed after 4 days but she
          inspected in order to exclude other intra­abdominal or
          pelvic pathology. The mesoappendix was transected by   Table 1: Modified Alvarado score (Ganesh Babu et al, 2012)
          diathermy after applying titanium hemoclip early in                                             Score
          this study but later on, blood vessel sealing device was   Symptoms  Migratory right iliac fossa pain  1
          used (ligasure 5 mm). The bases of the appendix were            anorexia                        1
          ligated with two endo­loops constructed with a Roeder’s         Nausea and or vomiting          1
          knot on a no­1 vicryl thread. The specimen was directly   Signs  Tenderness in right iliac fossa  2
          extracted or placed in an endo­bag and then extracted.          Rebound tenderness              1
          All specimens were sent for histopathology. Drain was           Elevated temperature            1
          inserted in patients with pus in the peritoneal cavity or       Extra signs; cough test, Rovsing sign  1
          with abscess formation.                              Laboratory  Leukocytosis                   2
                                                               Total score
                                                                                                          10
             Prior to the surgery, all the patients received a   Interpretation: Score 1 to 4: Acute appendicitis very unlikely;
          standard regimen of intravenous antibiotics (1.5 gm of   Score 5 to 7: Acute appendicitis probable; Score 8 to 10: acute
          cefuroxime). Further antibiotic regimen was determined   Appendicitis definitive
          according­to­the­operative­findings.                    Table 2: Demographic data, clinical presentation and
             The parameters examined in this study included:                comorbidities of the patients
          operation time (from skin incision to wound closure),   Age     Range         12-65 years
          conversion­to­open­procedure,­intraoperative­findings­          Mean ± SD     23 ± 11.65 years
          and length of hospital stay. Complications included   Sex       Male          151
          wound infections, intra­abdominal abscess, as well as           Female        422           Total = 573
          30 day readmission for complications.               Clinical    Alvarado score  466
             The discharge criteria included: afebrile patient with   presentation  ≥ 8               Total = 573
                                                                          Alvarado score  107
          audible bowel sounds and were able to tolerate a liquid         5­7
          diet.                                               Comorbidities  DM         34
             Statistical analysis was performed using SPSS statis­        HCV           25
          tical­software,­version­12.0­(SPSS­Inc,­Chicago,­IL).­The­      Pulmonary     18            Total = 77
          data were expressed as mean and standard deviation.             disease

          World Journal of Laparoscopic Surgery, September-December 2014;7(3):116-120                      117
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