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WJOLS
Can Intraperitoneal Tramadol decrease Pain in Patients undergoing Laparoscopic Cholecystectomy in Postoperative Period?
tramadol can be used safely at doses as in our study in preoperative symptoms and intraoperative events. Surg
intraperitoneally, which can be correlated with study Endosc 1994 Feb;8(2):90-96.
done by Akinci et al. 13 8. Joshipura VP, Haribhakti SP, Patel NR, Naik RP, Soni HN,
Patel B, Bhavsar MS, Narwaria MB, Thakker R. A prospective
randomized, controlled study comparing low pressure versus
CONCLUSION high pressure pneumoperitoneum during laparoscopic
cholecystectomy. Surg Laparosc Endosc Percutan Tech 2009
Intraperitoneal tramadol significantly reduces pain scores Jun;19(3):234-240.
in early postoperative period (4 hours in our study), 9. Roberts KJ, Gilmour J, Pande R, Nightingale P, Tan LC,
and requirement of rescue analgesic for first 8 hours Khan S. Efficacy of intraperitoneal local anaesthetic tech-
without significantly increasing incidence of adverse niques during laparoscopic cholecystectomy. Surg Endosc
effect or hemodynamic complications. So, it can be safely 2011 Nov;25(11):3698-3705.
introduced for control of postoperative pain in patients 10. Barczynski M, Konturek A, Herman RM. Superiority of
preemptive analgesia with intraperitoneal instillation of
undergoing laparoscopic cholecystectomy. bupivacaine before rather than after the creation of pneumo-
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