Page 44 - World Journal of Laparoscopic Surgery

Use of Laparoscopic vs Open Repair for Perforated Peptic Ulcers
Table 1: Patient demographics
All Laparoscopic Open
N = 219 N = 52 N = 167 p overall
Sex, N (%)
Female 108 (49.3%) 28 (53.8%) 80 (47.9%)
Male 111 (50.7%) 24 (46.2%) 87 (52.1%)
Age, median 62.6 (53.6; 74.6) 59.9 (53.3; 73.0) 63.0 (54.4; 74.7) 0.394
(25th; 75th)
BMI, median 26.3 (22.6; 31.2) 26.4 (22.9; 30.7) 26.2 (22.5; 31.3) 0.614
(25th; 75th)
Medication use: N (%)
PPI 32 (14.6%) 11 (21.2%) 21 (12.6%) 0.192
NSAIDs 64 (29.2%) 16 (30.8%) 48 (28.7%) 0.916
Immunosuppressant 32 (14.6%) 7 (13.5%) 25 (15.0%) 0.965
Anticoagulation 18 (8.22%) 3 (5.77%) 15 (8.98%) 0.574
Comorbidities: N (%)
COPD 28 (12.8%) 7 (13.5%) 21 (12.6%) 1.000
DM 35 (16.0%) 7 (13.5%) 28 (16.8%) 0.725
HTN 119 (54.3%) 27 (51.9%) 92 (55.1%) 0.810
CHF 17 (7.76%) 3 (5.77%) 14 (8.38%) 0.768
CKD 13 (5.94%) 2 (3.85%) 11 (6.59%) 0.738
Cirrhosis 8 (3.65%) 0 (0.00%) 8 (4.79%) 0.203
Previous H. pylori 6 (2.74%) 0 (0.00%) 6 (3.59%) 0.340
Previous surgery, N (%) 77 (36.3%) 22 (44.9%) 55 (33.7%) 0.210
PPI, proton pump inhibitor; NSAIDs, nonsteroidal anti-inflammatory drugs; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus;
HTN, hypertension; CHF, congestive heart failure; CKD, chronic kidney disease

Table 2: Clinical presentation data
All Laparoscopic Open
N = 219 N = 52 N = 167 p overall
Hospital setting N (%)
Community 116 (53.0%) 33 (63.5%) 83 (49.7%) 0.115
Tertiary 104 (47.5%) 20 (38.5%) 84 (50.3%) 0.182
Vitals
Median (25th; 75th)
Heart rate 85.0 79.0 86.0 0.050
(74.0; 95.5) (70.0; 93.2) (75.5; 97.0)
Respiratory rate 18.0 18.0 18.0 0.068
(18.0; 20.0) (16.0; 18.0) (18.0; 20.0)
Temperature (F) 98.1 98.0 98.1 0.629
(97.7; 98.6) (97.7; 98.4) (97.7; 98.6)
SBP (mm Hg) 127 127 127 0.803
(112; 140) (115; 139) (112; 140)
DBP (mm Hg) 70.0 68.0 71.0 0.299
(60.0; 79.0) (59.0; 76.2) (60.0; 80.5)
Lab values
Median (25th; 75th)
WBC 13.2 13.9 13.1 0.842
(8.85; 20.6) (9.19; 25.8) (8.71; 20.1)
Hgb 12.5 12.9 12.3 0.946
(10.2; 14.3) (10.1; 14.3) (10.4; 14.2)
Plt 271 282 268 0.288
(200; 368) (227; 375) (194; 366)

42 World Journal of Laparoscopic Surgery, Volume 15 Issue 1 (January–April 2022)