Page 45 - World Journal of Laparoscopic Surgery

Use of Laparoscopic vs Open Repair for Perforated Peptic Ulcers

1 Abnormal Hgb, N (%) 48 (21.9%) 12 (23.1%) 36 (21.6%)
2 Hypotension, N (%) 9 (4.11%) 0 (0.00%) 9 (5.39%)
3 Normal INR, N (%) 156 (90.7%) 33 (94.3%) 123 (89.8%)
Sepsis, N (%) 79 (36.1%) 15 (28.8%) 64 (38.3%) 0.281
Ulcer location, N (%) 0.029
Stomach 94 (42.9%) 15 (28.8%) 79 (47.3%)
Duodenum 125 (57.1%) 37 (71.2%) 88 (52.7%)
Preoperative CT scan, N (%) 193 (88.1%) 46 (88.5%) 147 (88.0%) 1.000
Image localized 130 (59.4%) 32 (61.5%) 98 (58.7%) 0.838
perforation, N (%)
Time of diagnosis, N (%) 0.376
4 Daytime 121 (55.3%) 32 (61.5%) 89 (53.3%)
5 Nighttime 98 (44.7%) 20 (38.5%) 78 (46.7%)
3
3
SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell (×10 /µL); Hgb, hemoglobin (g/dL); Plt, platelets (×10 /µL); INR,
international normalized ratio; 1, any deviation from normal range for age and sex; 2, SBP <90 mm Hg; 3, INR >2; 4, between 7 am and 7 pm; 5, 7 pm 7 am
Table 3: Surgeon demographics
All Laparoscopic Open
N = 219 (%) N = 52 (%) N = 167 (%) p overall
Residency graduation after 2006 122 (55.7%) 32 (61.5%) 90 (53.9%)
Residency hospital type
Community 77 (35.2%) 12 (23.1%) 65 (38.9%)
Tertiary 142 (64.8%) 40 (76.9%) 102 (61.1%)
Fellowship 133 (60.7%) 33 (63.5%) 100 (59.9%) 0.765
MIS fellowship 56 (25.6%) 24 (46.2%) 32 (19.2%) <0.001
MIS, minimally invasive surgery

Table 4: Final stepwise regression analysis
Group = “Laparoscopic” Group = “Laparoscopic”
Predictors Odds ratios CI p Odds ratios CI p
(Intercept) 0.14 0.00–6.96 0.328 0.07 0.02–0.31 <0.001
Age 0.99 0.97–1.02 0.481
Sex: Male vs Female 0.79 0.37–1.70 0.545
BMI 1.05 1.00–1.11 0.050 1.05 1.01–1.10 0.027
PPI: Yes vs No 1.68 0.64–4.39 0.292
NSAID: Yes vs No 0.81 0.37–1.77 0.591
Immunosuppression: Yes vs No 0.79 0.28–2.29 0.670
Anticoagulation use: Yes vs No 0.77 0.18–3.28 0.726
Comorbidity: Yes vs No 0.47 0.20–1.13 0.091 0.50 0.24–1.02 0.056
Previous surgery: Yes vs No 1.53 0.69–3.39 0.300
Surgeon graduation: 2006 and After vs 1.13 0.51–2.54 0.760
Before 2006
Residency type: Tertiary vs Community 2.31 0.98–5.45 0.057 2.23 0.97–5.11 0.058
Fellowship: Yes vs No 0.32 0.12–0.86 0.024 0.35 0.14–0.87 0.024
MIS fellow: Yes vs No 5.36 1.99–14.42 0.001 6.42 2.63–15.66 <0.001
DBP 1.00 0.97–1.03 0.746
Preoperative CT scan : Yes vs No 1.61 0.47–5.52 0.448
Imaging localization: Yes vs No 0.78 0.35–1.71 0.528
Hemoglobin: Normal vs Abnormal 0.93 0.39–2.21 0.876
Septic: Yes vs No 0.68 0.32–1.45 0.314
Ulcer location: Duodenum vs Stomach 1.45 0.65–3.26 0.368
(Contd...)

World Journal of Laparoscopic Surgery, Volume 15 Issue 1 (January–April 2022) 43