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Preoperative Prediction of Difficult Laparoscopic Cholecystectomy
            Table 4: Univariate analysis of preoperative factors compared to the final outcome of the surgery
                                                                Result
            Preoperative factors        Findings        Easy         Difficult      p value     Odds ratio
            Age                         Age <50 years   47 (46.1%)   16 (15.7%)     0.002       3.801 (1.625–8.89)
                                        Age >50 years   17 (16.7%)   22 (21.6%)
            Gender                      Female          55 (53.9%)   32 (31.4%)     0.812       1.146 (0.373–3.516)
                                        Male             9 (8.8%)     6 (5.9%)
            H/o acute cholecystitis     Absent          60 (58.8%)   10 (9.8%)      <0.0001        42 (12.11–145.612)
                                        Present          4 (3.9%)    28 (27.5%)
            H/o dyspepsia               Absent          26 (25.5%)   11 (10.8%)     0.236       1.679 (0.710–3.97)
                                        Present         38 (37.3%)   27 (26.5%)
            Diabetes mellitus           Absent          62 (60.8%)   27 (26.5%)     <0.0001     12.630 (2.62–60.88)
                                        Present          2 (2.0%)    11 (10.8%)
            Hypertension                Absent          48 (47.1%)   30 (29.4%)     0.65         0.80 (0.305–2.09)
                                        Present         16 (15.7%)    8 (7.8%)
            Previous abdominal surgery  Absent          47 (46.1%)   35 (34.3%)     0.022       0.237 (0.064–0.872)
                                        Present         17 (16.7%)    3 (2.9%)
            Previous ERCP               Absent          63 (61.8%)   34 (33.3%)     0.043        7.41 (0.796–68.97)
                                        Present          1 (1.0%)     4 (3.9%)
            BMI                         <27.5           46 (45.1%)   16 (15.7%)     0.003        3.51 (1.51–8.16)
                                        >27.5           18 (17.6%)    2 (1.6%)
            Murphy’s sign               Absent          36 (35.3%)   10 (9.8%)      0.003        3.60 (1.50–8.63)
                                        Present         28 (27.5%)   28 (27.5%)
            Palpabale gallbladder       Absent          64 (62.7%)   31 (30.4%)     <0.0001     NA
                                        Present          0 (0%)       7 (6.9%)
            USG: gallbladder wall thickness  <4 mm      62 (60.8%)   23 (22.5%)     <0.0001     20.21 (4.28–95.35)
                                        >4 mm            2 (2.0%)    15 (14.7%)
            Pericholecystic fluid       Absent          64 (62.7%)   35 (34.3%)     0.023       NA
                                        Present          0 (0%)       3 (2.9%)
            USG: impacted stone         Absent          52 (51.0%)   20 (19.6%)     0.002        3.90 (1.59–9.53)
                                        Present         12 (11.8%)   18 (17.6%)
            USG: contracted             Absent          63 (61.8%)   32 (31.4%)     0.006       11.81 (1.36–102.36)
                                        Present          1 (1.0%)     6 (5.9%)
                                        Count           23 (28.8%)   16 (20.0%)



























            Figs 1A and B: ROC curves of Randhawa et al. scoring system (A) showing with the area under the curve of 87.4% whereas the area under curve
            of proposed scoring system (B) is 94.5%

             36   World Journal of Laparoscopic Surgery, Volume 14 Issue 1 (January–April 2021)
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