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Non-appendicitis Pathologies during Appendectomy
            The dose of radiation delivered to the patients during CT scan of   In this study, histopathology of the removed appendix was done
            the abdomen is high, which may be comparable to 400 chest X-rays,   for all cases. 131 (90.34%) patients had appendiceal pathology, 130
            and this certainly will increase the risk of occurrence of malignancies   (89.66%) patients had different types of acute inflammations, and
            like leukemia. 8–10                                one patient had a low-grade mucinous neoplasm non-infiltrative
               In our institution, a CT scan is not routinely used to diagnose   with free margins. Fifteen patients had negative appendectomies.
            acute appendicitis.                                The appendix of the patient with cecal diverticulitis showed acute
               Acute appendicitis can mimic many gynecologic conditions,   catarrhal inflammation. Six patients with negative appendectomy
            making the diagnosis uncertain. Although the imaging techniques   had another pathology of their acute abdominal pain, which
            have improved over the last three decades, it may still be challenging   managed laparoscopically. Nine (6%) patients had no apparent
            to differentiate between non-gynecologic and gynecologic causes   cause of their abdominal pain.
            of the acute abdomen before surgery. 11               Appendiceal mucinous neoplasms are rare tumors with an
               This retrospective study was done on 145 patients who were   incidence of 0.4–1.0% among gastrointestinal cancers. In the early
            admitted to the Emergency Unit, Zagazig University Hospitals,   stage and due to distension of the appendix with mucin, it presents
            Egypt with a diagnosis of acute appendicitis from March 2017 to   with acute appendicitis-like symptoms. About one-third of the
            December 2019.                                     patients with appendiceal mucinous neoplasms are diagnosed
               In this study, the incidence of non-appendicitis acute abdomen   preoperatively as acute appendicitis. 23,24
            among our patients was 7/145 (4.83%). The gynecological causes   The incidence of non-appendicitis pathology in our study was
            were 4/145 (2.76%): three ruptured ovarian cysts, and one ovarian   7/145 (4.83%), which was slightly higher than that reported by
            torsion. The extra-appendiceal non-gynecological causes were   Yabanoglu et al. (3.9%). 4
            3/145 (2.07%): one Meckel’s diverticulitis, one cecal diverticulitis,
            and one inflamed sigmoid appendices epiploica.     conclusIon
               Seetahal et al. conducted a retrospective study that revealed
            that the gynecologic conditions involving the ovary are the   Diagnosis of acute appendicitis is challenging up to date; we faced
            commonest to be misdiagnosed as an appendiceal disease in   many conditions mimicking acute appendicitis during surgical
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            females.  Literature depicted the risk of a wrong preoperative   intervention.
            diagnosis (ovarian causes versus acute appendicitis) to be 5–8%,
            which was not high but still worthy of attention. 13  orcId
               The clinical presentation of Meckel’s diverticulitis is typically   Mohammed Algazar   https://orcid.org/0000-0001-7307-8579
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            nonspecific.  Radiologically, the diagnosis of Meckel’s diverticulitis
            can be challenging, especially if it is initially not suspected. 15  references
               In this study, one case (0.69%) of complicated gangrenous
            Meckel’s diverticulitis was detected in a 31-year-old male who     1.  Sartelli M, Baiocchi GL, Di Saverio S, et al. Prospective observational
            presented with right iliac fossa pain and leukocytosis, and   study on acute appendicitis worldwide (POSAW). World J Emerg Surg
                                                                    2018;13(1):19. DOI: 10.1186/s13017-018-0179-0.
            ultrasonography showed only free fluid in the right iliac fossa.    2.  Vellei S, Borri A. Single-incision versus three-port laparoscopic
               Epiploic appendagitis of the sigmoid colon is a rare cause of   appendectomy: short- and long-term outcomes. J Laparoendosc
            acute abdominal pain. The cause of this pathology may be torsion   Adv Surg Tech 2017;27(8):804–811. DOI: 10.1089/lap.2016.0406.
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            or thrombosis of the appendage’s veins.  It is often misdiagnosed     3.  Cheng H-T, Wang Y-C, Lo H-C, et al. Laparoscopic appendectomy
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            as either appendicitis or diverticulitis, according to its location.    versus open appendectomy in pregnancy: a population-based
            Two studies found that the most common presentation of epiploic   analysis of maternal outcome. Surg Endosc 2015;29(6):1394–1399.
            appendagitis was left lower quadrant pain (69–89%), right lower   DOI: 10.1007/s00464-014-3810-5.
            quadrant pain (8–16%), and pain at other locations, including in     4.  Yabanoglu H, Caliskan K, Aytac HO, et al. Unusual findings in
                                                                    appendectomy specimens of adults: retrospective analyses of
            right and left upper quadrants (1.5–3%). 18,19          1466 patients and a review of literature. Iran Red Crescent Med J
               In our study, one case (0.69%) was detected in a 33-year-old   2014;16(2):e12931–e12931. DOI: 10.5812/ircmj.12931.
            male who presented with right iliac fossa pain mimicking acute     5.  Karam AR, Birjawi GA, Sidani CA, et al. Alternative diagnoses of acute
            appendicitis that started a week before the presentation.  appendicitis on helical CT with intravenous and rectal contrast. Clin
               Inflammation  of  a  colonic  diverticulum  in  the  caecum   Imaging 2007;31(2):77–86. DOI: 10.1016/j.clinimag.2006.12.023.
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            or ascending colon is called right-sided diverticulitis.  The     6.  Howell JM, Eddy OL, Lukens TW, et al. Clinical policy: critical issues in
            presentation of cecal diverticulitis is usually acute abdominal   the evaluation and management of emergency department patients
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            appendicitis. The treatment of the cecal diverticulum in most      7.  Petroianu A. Diagnosis of acute appendicitis. Int J Surg 2012;10(3):115–
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            hemicolectomy. 21                                    8.  Mettler FA, Huda W, Yoshizumi TT, et al. Effective doses in
               In this study, we encountered a case of cecal diverticulitis in   radiology and diagnostic nuclear medicine: a catalog. Radiology
            a 44-year-old female during laparoscopic appendectomy that   2008;248(1):254–263. DOI: 10.1148/radiol.2481071451.
            was managed conservatively, and the patient improved and was     9.  Guite KM, Hinshaw JL, Ranallo FN, et al. Ionizing radiation in
            discharged after three days postoperatively.            abdominal CT: unindicated multiphase scans are an important source
               Oudenhoven et al. reported the success of the conservative   of medically unnecessary exposure. J Am Coll Radiol 2011;8(11):756–
                                                                    761.   DOI: 10.1016/j.jacr.2011.05.011.
            medical treatment in most of the cases with cecal diverticulitis     10.  Markar SR, Karthikesalingam A, Cunningham J, et al. Increased use
            (41/44) and surgery in three patients. The symptoms recurred in   of pre-operative imaging and laparoscopy has no impact on clinical
            five patients who received the medical treatment, two of them   outcomes in patients undergoing appendicectomy. Ann R Coll Surg
            needed surgical treatment. 22                           Engl 2011; 93(8):620–623. DOI: 10.1308/003588411X13165261994076.

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