Page 15 - World Journal of Laparoscopic Surgery
P. 15

Role of Laparoscopic Surgery in Endometriosis Associated Infertility—Literature Review

            RESULTS                                            The studies in the Table 2 include observational studies,
            Table 2 shows the various studies which looked for the effect  randomized controlled studies and non randomized studies
            of laparoscopic surgery on endometriosis associated infertility.  which can be retrospective or prospective in nature.


             TABLE 2: Laparoscopic surgery on endometriosis associated infertility
             Author        Sample Classification  Selection criteria  Intervention  Follow-up     Outcome
                           size                                                         PR    LBR   MR     ER
             Martin 1985   50                Endometriosis,  Lap CO 2  laser  7-19 months  60%      (1)    (1)
             (abstract only)                 Other infer
                                             factors

             Seiler et al 1986  90  Acosta   Moderate endomet  Lap electrocautery, 7  months  44%
                                                             Danazol                    39%
             Martin 1986   115               Endometriosis,  Lap CO  laser  12-44 months  48%  69%  28%    1%
                                                                  2
             (abstract only)                 Other infer factors
             Donnez 1987   124    Acosta     Endometriosis   Lap laser,     18  months        52%   (3/124) nil
                                             Adnexal adhesion  adhesiolysis

             Sutton et al 1990  56  rAFS     Endometriosis alone Lap laser  1-6 years   80%   69%
             Adamson et al 1992 27  rAFS     Endometriosis             Laparoscopy,  2 years  29.6%
                                             Other infer factors  Laparotomy            23.7%
             Dlugi et al 1992  74  rAFS      Endometriosis   Lap  KTP laser  24  months  38%
                                             Other infer factors

             Hull et al 1992                 Severe          Lap laser,     2 years     50%
                                             Endometriosis   Laparotomy

             Adamson et al  575   rAFS       Endometriosis   Laparoscopy,    > 3 years  82%
             1993                            Other infer     Laparotomy, no or
                                             Factors         Medical  treatment

             Hughes et al         Acosta     Endometriosis   Laparoscopy,
             1993                 rAFS       Endometrioma    Laparotomy
             Adamson and          Acosta     Endometriosis   Laparoscopy,   3 years     44+/-6%
             Pasta 1994           rAFS       Endometrioma    Laparotomy     52+/-9%
             Beretta et al  64    rAFS       Endometrioma    Lap Excision,  24  months  66.7%
             1998                            >/ = 3 cm       Lap coagulation            23.5%

             Hemmings et al  156  rAFS       Endometrioma >3cm Lap Excision,  36  months  60%
             1998                            Stage 3 and     Lap ablate
                                             4 endometr
                                             Laparotomy
             Milingos et al  64   rAFS       Endometrioma    Lap  cystectomy  2 year    53%
             1998                            >/ = 3 cm       Adhesiolysis

             Chapron  et al 1999  30  rAFS   Endometriosis only  Lap resect, ablate  12  months  46%  (12)  (3)
             Maruyama et al  186  rAFS       Endometriosis   Lap excision,  18  months  27.6%
             2000                            Tubal adhesion +/-  tubal adhesiolysis
                                                                                                           Contd...


                                                             13
   10   11   12   13   14   15   16   17   18   19   20