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WJOLS


                                          Gastric Plication as a New Stand-Alone Procedure for the Treatment of Morbid Obesity

                                                              b.  Gastric obstruction (0.4%):
                                                                 •    Due to gastric fold invagination into the lower eso-
                                                                    phagus (0.2%)
                                                                 –  Treated by laparoscopic deplication and a looser
                                                                       gastric plication was performed.
                                                                 •  Due to gastric fold invagination into the pylorus (0.2%)
                                                                 –  Treated by deplication.
                                                              c.  Gastrogastric herniation (0.6%):
                                                                 •  Leading to esogastric leak and peritonitis (0.2%)
                                                                 –  Treated by laparoscopic deplication, gastric suture
                                                                       and looser plication.
                                                                 •  Leading to gastric hernia necrosis and peritonitis
                                                                    (0.2%).
                                                                 –  Treated by gastric resection of necrotic herniation,
                                                                       and deplication.
          Graph 1: Clinical data summary by  30 < BMI < 45 and BMI > 45:
          EWL%  is 31.98% vs 21.56% at 1 month (p < 0.001); 49.57% vs     •  Leading to late gastric obstruction at 4 months (0.2%).
          35.15% at 3 months (p < 0.001); 66.17% vs 48.79% at 6 months      –  Deplication
          (p  < 0.001)  and  70.82%  vs  57.47%  at  12  months  (p  < 0.001).
          However, after 12 months, a significant difference is noted    d.  Gastric leak over a stitch (0.2%)
          between the subgroups, because of a slight trend to an additional     •  Deplication and gastric suture
          increase in %EWL in the subgroup of BMI between 30 and 45,     e.  Subphrenic abscess (0.2%)
          and a slight decrease in %EWL in the subgroup of BMI > 45
          (p < 0.001)                                            •  CT-guided percutaneous drain
                                                              f.  Gastric bleeding by gastric ulcers at 2 months (0.2%).
          different periods. This result is similar to that seen in the
                                                                 •  Blood transfusion, endoscopic sclerosis with PPI
          overall group independent of the BMI, with higher degrees of     g.  Portomesenteric thrombosis (0.4%)
          EWL in the separated sutures subgroup. However, no com-     •  One case treated by thrombolysis and heparino-
          parison is done at 18 months because, up to this date, no patient   therapy
          in the separated suturing subgroup has reached this period      •  One case treated by intestinal resection and heparino-
          (Graph 3).
                                                                    therapy
          complications                                       h.  Gastric line suture rupture and re-expansion (1.78%).
                                                                 •  Seven cases treated by replication (delayed reinterven-
          Major Surgical Complications                              tion).
          a.  Peroperative massive bleeding due to mesenteric trocar     •  One case treated by sleeve gastrectomy (delayed
             lesion (0.2%):                                         reintervention).
             •  Treated by laparotomy for hemostasis and open     In total:
                LGCP was achieved.                               •  Six cases (1.38%): acute early reintervention.

                        Table 4: Subgroup 1: Gastric plication with continuous suturing at the first/second rows (n = 183)
            Time (months)              Number of patients (N)    Average % EWL ± standard deviation  p-value
            1                          173                       28.67 ± 9.8
            3                          161                       44.78 ± 13.5                       < 0.001*
            6                          158                       60.25 ± 18.6                       < 0.001*
            12                         146                       66.71 ± 17.5                       0.002*
            18                         42                        66.42 ± 18.2                       0.92
           *Statistically significant
            Table 5: Subgroup 2: Gastric plication with separated stitches in the first row with anterior and posterior marks over a 36 Fr tube,
                                        and the second row with continuous suturing (n = 186)
           Time (months)              Number of patients (N)         Average % EWL ± standard deviation  p-value
           1                          142                            32.87 ± 11.6
           3                          121                            52.61 ± 14.2                    < 0.001*
           6                          83                             71.81 ± 19.7                    < 0.001*
           12                         20                             80.77 ± 20.3                    0.07
           *Statistically significant
          World Journal of Laparoscopic Surgery, May-August 2014;7(2):49-59                                 57
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