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WJOLS



                    A Comparison of Combined Laparoscopic Uterine Artery Ligation and Myomectomy vs Laparoscopic Myomectomy

                         Table 1: Comparison of various studies in term of operative time and intraoperative blood loss
                                                                                      Outcome Intraoperative
                                               No. of participants        Operating time (min)  blood loss (ml)
                                                                            Control
                              Experimental  Control            Experimental   group    Experimental   Control
           Study name         group (E)   group (C)  Total     group (E)    (C)        group (E)     group (C)
           Saeed Alborzi et al  65        87        152        112 ± 18     95 ± 14   173 ± 91       402 ± 131
           Chin-Jung Wang et al  20       —         20         120 (100–148)  —       100 (56.3-137.5) —
           Ji Hae Bae et al   51          39        90         100 ± 33.8   90 ± 37.1  72.3 ± 109    62.6 ± 77.3
           Z Holub et al      15          16        31         76.5         69.6      93.7           134
           Giuseppe Vercellino   80       86        166        —            —         1.2 g/dl       1.45 g/dl
           et al
           E: Experimental group, C: Control group
          are permanent methods and might not be suitable for     In experimental group there is decrease in incidence
          women who want to retain their childbearing capacity.  of recurrence rate of myoma and blood transfusion com-
          Hem-o-lok clips can stop uterine blood flow at the uterine  pared to contol group.
          artery level and reperfusion occurs after removal. With
          the aid of this instrument, blood loss can be controlled  ConCLUSion
          and childbearing preserved when performing a uterine
          depletion procedure followed by a myomectomy.       In conclusion, LM offers several benefits to the patient. It
             Criticisms of the transient blocking uterine perfu-  is still a challenging technical procedure and might be
                                                              associated with high surgical morbidity and incidence
          sion procedure are that the average 2 hours occlusion
          time might induce irreversible damage in the uterine   of blood transfusion. Surgical strategies are needed to
          myometrium and cause embolic events and pulmonary   overcome these problems in LM.
                                                                 Uterine artery ligation prior to myomectomy can

          emboli after release of the clips.                  control operative blood loss in LM and preserve the
             Traditional uterine tourniquets usually require only   childbearing capacity of the patient, However, larger
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          an hour.  A review of the literature on ischemic, necrotic   studies to investigate the feasibility and effectiveness of
          twisted adnexa showed no reports of embolic pheno-  this procedure are crucial before definite conclusions can
          mena after detorsion. 23,24  In addition, the uterus has a   be drawn.
          dual extrinsic blood supply. The primary supply is from
          the uterine arteries, and the secondary supply is from   REFEREnCES
          branches of the ovarian arteries. If the uterine arteries
          are occluded, the myometrium is supplied by the ovarian      1.  Liu WM, Wang PH, Chou CS, Tang WL, Wang IT, Tzeng CR.
          arteries through the communicating arteries. If the ova-  Efficacy of combined laparoscopic uterine artery occlusion
          rian arteries remain intact during the operation, damage   and myomectomy via minilaparatomy in the treatment of
                                                                  recurrent uterine myomas. Fertil Steril 2007;87(2):356-361.
          to the myometrium theoretically would not occur, regard-    2.  Kirsten H, Anton L, Nils EK, Hans JN, Anette BB, Olav I.
          less of the length of time the uterine arteries are occluded.  Laparoscopic occlusion of uterine vessels for the treatment of
             Blood loss in myomectomy mainly occurs during        symptomatic fibroids: initial experience and comparison to
          removal of fibroids and uterine repair. Therefore, it is   uterine artery embolization. Am J Obstet Gynecol 2004;190(1):
                                                                  37-43.
          necessary to quickly suture the wound to avoid a massive     3.  Park K, Kim J, Shin J, Kwon J, Koo J, Jeong K. Treatment
          hemorrhage. It is not easy to perform a perfect uterine   outcome of uterine artery embolization and laparoscopic
          repair with minimal blood loss within a short time in   uterine artery ligation for uterine myoma. Yonesei Med J
          laparoscopic surgery unless surgeons are proficient in   2003;44(4):694-702.
          laparoscopy. A uterine depletion procedure can provide a     4.  Liu WM, Ng HT, Wu YC, Yen YK, Yuan CC. Laparoscopic
          relatively bloodless situation and let the surgeon perform   bipolar coagulation of uterine vessels: a new method for
                                                                  treating symptomatic fibroids. Fertil Steril 2001;75(2):417-422.
          laparoscopic suturing with ease.                      5.  Campo S, Garcea N. Laparoscopic myomectomy in premeno-
             After reviewing literature on uterine artery ligation   pausal women with and without preoperative treatment
          prior to laparoscopic myomectomy shows that it signi-   using gonadotrophin-releasing hormone analogues. Hum
          ficantly reduces blood loss compared to laparoscopic my-  Reprod 1999;14(1):44-48.
          omectomy without uterine artery ligation group (Table 1).    6.  Pokras R, Hufnagel VG. Hysterectomies in the United States
             All of the studies also show that it slightly increases   1965–1984. Vital health statistics, series 13.92. Washington,
                                                                  DC: US Government Printing Office; March 1987.
          in operative time without any increase in morbidity in     7.  Liu WM, Tzeng CR, Yi-Jen C, Wang PH. Combining the
          experimental group (Table 1).                           uterine depletion procedure and myomectomy may be useful
          World Journal of Laparoscopic Surgery, May-August 2015;8(2):52-56                                 55
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