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Laparoscopic vs Mini-incision Open Appendectomy
            Table 2: Comparison based on postoperative complications in two groups
                                                 Group MIA                         Group LA
             Postoperative complications  Number of patients   %          Number of patients    %          p-value
             Wound infection                   6              11.5              0               0.0        0.027*
             Adhesion obstruction              3               5.8              0               0.0        0.243
             Intra-abdominal abscess           2               3.8              1               2.0        1.000
             Ileus                             4               7.7              0               0          0.118
            *Statistically significant difference (p <0.05)
               Complications were seen in 11 patients who underwent MIA.   Wound infection is the most common postoperative compli-
            It included wound infection in 6 (11.5%), intra-abdominal abscess   cation seen in 5–10% patients after open appendectomy. The other
            in 2 (5.8%) and ileus in 3 (7%) patients (Table 2). On the other hand,   complications reported include intra-abdominal abscess (8%) and
            only one patient with LA had a postoperative complication in the   ileus mostly seen following removal of gangrenous appendix.
            form of intraabdominal abscess. The difference between the two   Another rare complication reported is the leakage from appendicular
            groups as far as the wound infections is concerned was statistically   stump, which may occur if the encircling stitch has been put too
            significant with p = 0.027 in favor of LA (Table 2).  deeply resulting into a faucal fistula. Subacute intestinal obstruction
               A total of 36 (73.5%) patients from LA group resumed orals   due to postoperative adhesions is most common late complication
            within 12 hours after surgery while more than 84% patients from   of open appendectomy.  Laparoscopic appendectomy combines
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            MIA group resumed orals 24 hours after surgery. The difference was   the advantages of diagnosis and treatment in one procedure. With
            statistically significant with p <0.001 in favor of LA.  the development of laparoscopic technique, it has been used for
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               All 52 patients belonging to MIA group had hospital stay for   both diagnosis and treatment of acute appendicitis.  Advantages
            more than 30 hours, while out of 49 patients belonging to LA   of LA include lower hospital stays, shorter recovery period, lower
            group, 44 (89.8%) had a hospital stay of less than 30 hours, and   postoperative pain, lower postoperative infections, and early
            remaining 5 (10.2%) patients had stay of more than 30 hours, which   return to daily activities. 14–16  Several prospective randomized
            was statistically significant with p <000.1. The 5 patients from LA   studies have been carried out to compare outcome of laparoscopic
            group who had hospital stay of more than 30 hours had delayed   and open appendectomy, and the overall differences have been
            onset of bowel sounds with postoperative abdominal distension,   found to be insignificant. The percentage of appendectomies
            which was managed conservatively.                  performed laparoscopically continues to increase.  In contrast to
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               In this study, 31 (63.3%) patients from LA group returned to   open appendectomy, patients with perforated appendicitis have
            routine work by 1 week while 2 (3.8%) patients from MIA group and   been reported to have lower rates of wound infections following
            16 (32.7%) patients from LA group returned to routine work by 1–2   laparoscopic procedure. 18
            weeks. On the other hand, 50 (96.2%) patients from MIA group and   In this study, the mean operative time in MIA group was 32.7
            2 (4.1%) patients from LA group returned to routine work after 2   (2.52) minutes while in LA group, the mean operative time was
            weeks. The p-value was statistically significant (<0.001) in favor of LA.  26.9 (2.46) minutes. Laparoscopic appendectomy was less time
                                                               consuming as compared to MIA with a significant p <0.001. The
            dIscussIon                                         results of this study were similar and comparable to the results of
            Surgical intervention is the most common modality of management   the study conducted by Özsan et al.  with a mean operative time of
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            for acute appendicitis. Gridiron incision is the most common   21.34 ± 8.39 in LA and a mean operative time of 28.32 ± 5.87 in MIA.
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            approach utilized when diagnosis of appendicitis is reasonably   This study was also comparable to Islam et al.  with an operating
            certain. In case the need arises, the gridiron incision may be   time of 33 (5.8) in LA and operating time of 37 (7.5) minutes in
            converted to a muscle cutting Rutherford Morison incision for better   MIA. The results of this study were not comparable to the study of

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            exposure. Another popular incision employed widely is a transverse   Naraintran et al.,  inwhich LA had taken a mean time of 68.5 (20.3)
            skin incision located approximately 2 cm below the umbilicus with   minutes and open appendectomy had taken a mean time of 48.2
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            its center on the mid-clavicular-mid-inguinal line. The exposure is   (12.4) minutes (p <0.001). In a study by Kushwah et al.,  the mean
            better with this type of incision and the incision may be extended   operating time was 60.8 and 45.7 minutes for laparoscopic and open
            medially either by retraction or by division of the rectus abdominis   appendectomy, respectively.
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            muscle if need arises.  Mini-incision appendectomy is done either   In this study, total of four patients from MIA group had bleeding
            in general or spinal anesthesia. For the mini-incision approach,   intraoperatively which was managed by electrocoagulation at the
            an abdominal examination is done and the most painful point is   same time, while none of the patients from LA group had bleeding
            identified and marked preoperatively. From that marked point, a   intraoperatively, with p = 0.118.
            2.5–3 cm oblique incision is made instead of classical McBurney’s   In this study, three patients from the MIA group had iatrogenic
            incision appendix is delivered through the incision by using an   injury (two had injury to caecum and one to terminal ileum) while
            index finger. Mesoappendix is identified and ligated by 2/0 silk   handling tissue which were repaired at the same time by primary
            suture and finally divided. Base of appendix is transfixed using 2/0   suturing and putting a drain. None of the patients in LA group had
            vicryl suture (Fig. 3). The knot at the base is further secured using   any iatrogenic injury (p = 0.243).
            2/0 silk suture to prevent stump leak. The peritoneum and fascia   In this study, the hospital stay was significantly less in those
            are approximated using 2/0 vicryl sutures. The incision in the skin   who underwent laparoscopy as compared to those who underwent
            is closed by using 1/0 non-absorbable suture.      MIA group with a statistically significant p <0.001 in favor of LA.


            196   World Journal of Laparoscopic Surgery, Volume 15 Issue 3 (September–December 2022)
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