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Single-port vs Traditional Laparoscopic Cholecystectomy
            observed in gynecologic, urologic, pediatric, gastrointestinal, and   bile duct diameter with no stones impacted, and so on. Laboratory
            bariatric surgery. 13                              investigations for patients in both groups were normal including
                                                               serum bilirubin, serum alkaline phosphatase, liver enzymes,
            PAtIents And Methods                               bleeding profile, and hemoglobin level. All cases with symptomatic
            All patients who had chronic calcular cholecystitis at the General   cholelithiasis and all surgeries were elective.
            Surgery department 7 at Mansoura University Hospital between   Operative time: In Group A, the mean operative time in minutes
            May 2014 and May 2018 were eligible for this study to compare   was 95.75 ± 18.37 (Table 2) whereas in the MPLC group, it was
            between SPLC and MPLC. Operative and perioperative outcomes,   42.10 ± 5.04, so that the mean operating time in Group B was
            including cosmesis and quality of life, were analyzed. Candidates   significantly lower than in the SPLC group (p <0.01).
            were randomly assigned into two groups: Group A consisted
            of 40 cases (single-port laparoscopic cholecystectomy) and   Operative times and learning curve: The  operative  time was
            Group B consisted of 40 cases (traditional multiport laparoscopic   significantly higher in Group A (Fig. 1). An important reduction in
            cholecystectomy).                                  the operative time was achieved as the number of cases undergoing
                                                               SPLC had increased. In the first 20 cases, the average operative
            Inclusion criteria: (1) age: ≥15 years, (2) sex: male and female, (3)   time was 100 minutes whereas in the second 20 patients, it was 80
            ultrasound finding of gallbladder stones, (4) biliary colic, and (5)   minutes (Fig. 2).
            BMI <40.
                                                               Intraoperative complications: In the SPLC group, we encountered
            Exclusion criteria: (1) age: <15 years, (2) acute pancreatitis, (3)
            common bile duct stones, (4) contraindications for single-port   intraoperative bleeding in one case. The source of bleeding was
            cholecystectomy, namely, ASA classification of 3 or 4 indicating   a cystic artery, and we had to convert to MPLC to control the
            pregnancy, and (5) BMI >40.                        bleeding whereas in the MPLC group there was no intraoperative
                                                               bleeding (p = 0.311) which is insignificant (Fig. 3). There was no
               All candidates underwent proper history taking, thorough   intraoperative viscus injury or bile leakage in both groups.
            clinical examination, radiological, and full laboratory investigation
            stressing on liver status.                         Conversion to MPLC: In the SPLC group (Fig. 4), the conversion to

            Follow-up of the patients: Follow-up of the patients included oper-  MPLC was mandated in five patients. In one patient, it was due
            ative time, periprocedural operative complications (bleeding, bile   to uncontrolled bleeding from a cystic artery. In two patients,
            leak, visceral injury, conversion to MPLC or open cholecystectomy).   conversion was due to a tense gallbladder with pericholecystic
            Postoperative follow-up included postoperative bleeding, bile    adhesions and exposure of Calot’s triangle was difficult. Both
            leak, hospital stay, wound infection, incisional hernia, and cosmesis   patients were male and had a history of recent attack of acute
            for one year. All of these data were collected, tabulated, and   cholecystitis. In one patient, there was a caterpillar hump anomaly
            analyzed carefully using SPSS version 26.          of the right hepatic artery occupying most of the cholecystohepatic
                                                               triangle and so we had to convert for better delineation of Calot’s
                                                               triangle and safe cholecystectomy. In one patient, we converted to
            results                                            MPLC then to open procedure due to a thick gallbladder with an
            This comparative prospective research was performed on all   impacted large stone at the cystic duct.
            eligible candidates who were classified into two groups: Group
            A consisted of patients who underwent single-port laparoscopic   Postoperative complications (bleeding, bile leak): In both groups, we
            cholecystectomy and Group B consisted of patients who underwent   did not have postoperative bleeding or bile leak.
            multiport laparoscopic cholecystectomy.
                                                               Postoperative pain and need for additional analgesia: All patients
            Demographic Criteria and Clinical Characteristics of   in both groups received the same postoperative analgesia
            the Patients                                       (paracetamol injection 8 hourly). In the SPLC group, the number
            Demographic and clinical characteristics of the patients are shown   of patients requiring additional analgesia in the form of NSAIDS
            in Table 1. Patients in both groups had same abdominal sonography   was 16 (40%) whereas in the MPLC group, the number of patients
            finding, such as normal liver, gallbladder stones, normal common   requiring additional analgesia was 30 (75%) (p = 0.025), indicating


                                    Table 1: Demographic and clinical characteristics of the patients
                                                        SPLC group  MPLC group
                                                         (n = 40)   (n = 40)   t     p
                                     Age (mean ± SD), years     37.35 ± 10.72 40.70 ± 9.71  1.036  0.307
                                     BMI (mean ± SD)   30.15 ± 4.53  28.35 ± 2.83  1.506  0.140
                                     Sex                No.    %   No.   %
                                      Male               8    20%   10  25%   0.143 #  0.705
                                      Female             32   80%   30  75%
                                     Recent attack of acute   6  15%  4  10%  0.229  0.633
                                     cholecystitis
                                     or pancreatitis


            222   World Journal of Laparoscopic Surgery, Volume 14 Issue 3 (September-December 2021)
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