Page 9 - WJOLS

Laparoscopic Ultrasound–Guided versus Percutaneous Radiofrequency Ablation in Treatment of Unresectable HCC

TABLE 2: Preoperative clinical, laboratory and radiological finding in the studied groups

Items Group I (PRFA) Group II (LUSRFA) Total P-value
Total number 30 30 60
Presentations:
= Right hypochondrial pain 14 (46.67%) 24 ( 80%) 38 (63.33%) 0.05
= Bleeding per gums 6 (20%) 6 (20%) 12 (20%) 1.0
= Epistaxis 6 (20%) 4 (13.33%) 10 (16.66%) 0.7
= Varices 2 (6.67%) 0 2 (3.33%) 0.3
= Dyspepsia 2 (6.67%) 0 2 (3.33%) 0.3
Biochemical Finding:
= Albumin gm/dl (mean) 3.1 2.7 2.9 + 0.4 0.000
= Bilirubin mg/dl (mean) 1.3 0.9 1.1 ± 0.22 0.000
= PPT seconds (mean) 32 33 32.5 ± 0.8 0.322
= Transaminases IU% (median) 90 62 76
= α-fetoprotein IU% (median) 307 362 334.5
Viral markers:
= HBs AG 4 (13.33%) 2 (6.67%) 6 (10%) 0.543
= HCV 24 (80%) 28 (93.33%) 52 (86.67%) 0.283
= HBs AG+HCV 4 (13.33%) 2 (6.67%) 6 (10%) 0.543

Tumor = One segment affected: 22 26 48
o Left lobe: 6 8 14
– Segment 2 2 (6.67%) 0 2 (3.33%)
– Segment 4 4 (13.33%) 8 (26.67%) 12 (20%)
o Right lobe: 16 18 34
– Segment 5 2 (6.67%) 6 (20%) 8 (13.33%) 0.37
– Segment 6 6 (20%) 8 (26.67%) 14 (23.33%) 0.143
– Segment 7 2 (6.67%) 2 (6.67%) 4 (6.67%) 0.309
– Segment 8 6 (20%) 2 (6.67%) 8 (13.33%) 0.143
= Two Segments 8 4 12
o Left and right lobes: 2 0 2
– Segment 4 and 7 2 (6.67%) 0 2 (3.33)
o Right lobe: 6 4 10
– Segment 5 and 7 4 (13.33%) 0 4 (6.67%)
– Segment 5 and 8 2 (6.67%)0 0 2 (3.33%):·
= Tumor size:
• Less than 3 cm. 8 (26.67%) 4 (13.33%) 12 (20%) 0.361
• 3 – 5 cm 22 (73.33%) 26 (86.67%) 48 (80%) 0.361
= Tumour Numbers:
• Single. 22 (73.33%) 26 (86.67%) 48 (80%) 0.361
• Two 8 (26.67%) 4 (13.33%) 12 (20%) 0.361

TABLE 3: Preoperative clinical TNM staging and child-Pugh classification in the studied groups

Items Group I (PRFA) Group II (LUSRFA ) Total P-value
Total number 30 30 60
Clinical staging (TNM):
• I 24 (80%) 26 (86.67%) 50 (83.33%) 0.830
• II 4 (13.3%) 2 (6.67%) 6 (10%)
• IIIa 2 (6.67%) 2 (6.67%) 4 (6.67%)
Child’s-Pugh classification:
• A 6 (20%) 10 (33.33%) 16 (26.67%) 0.4
• B 24 (80%) 20 (66.67%) 44 (73.3%)

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