Page 19 - World Journal of Laparoscopic Surgery
P. 19

R Dennis et al
            as a postoperative bile leak managed by laparoscopy, washout  DISCUSSION
            and laparoscopic repair of a CBD injury. The second, a hepatic  This series demonstrates that laparoscopic cholecystectomy is
            duct injury complicating laparoscopic bile duct exploration, was  safe and efficacious in the patients over 80 years. Thirty seven
            recognized at the time of surgery and repaired laparoscopically.  (54%) of our patients with an age range 80 to 91 years left
            The grade 2 complications are summarized in Table 4.  hospital within 5 days without complications from surgery.
               Subgroup analyses were performed for the cases converted
            to open surgery and those having grade 2 complications. These  Symptomatic gallstones can have a significant impact on an
            two groups were compared to the remainder of the cohort for  individual’s quality of life and with the increasing life expectancy
            significant differences in ASA grade (> III), age, sex,  and quality of health of octogenarian patients, a substantial
            complications of gallstone disease, difficulty of dissection,  number will realize the benefits of surgery.
            timing of surgery and grade of operating surgeon. The converted  Our conversion rate of 7.3% compares favorably with
            cases had significantly higher incidences of emergency surgery  previous studies. Lower conversion rates (2.2%) have only been
            and difficult dissections (Table 5). For patients with grade 2  quoted for cohorts with a small proportion of urgent cases
            complications there was a significant difference in the history  (4.4%). The importance of the learning curve of the operating
            or presence of CBD stones (Table 6).               surgeon is well-documented for the incidence of bile duct injury,
                                                               conversion rates and morbidity associated with laparoscopic
              Table 4: Summary of grade 2 complications from laparoscopic  cholecystectomy.  Increasing confidence and experience in the
                                                                             8
                            cholecystectomy (n = 8)
                                                               techniques of laparoscopic dissection are likely to have
            Grade 2 complication    Intervention     Number of  contributed to the low conversion rate in this series. An
                                                      cases
                                                               improvement in conversion rates over time has been noted
            Postoperative hemorrhage  Blood transfusion  2 (3%)  previously for elderly patients (65-79 years) although not in
            Postoperative hemorrhage  Laparotomy and  2 (3%)   patients over 80 years. 6
            and peritonism          washout of hematoma           Whilst we have shown favorable outcomes this data does
            Postoperative peritonism  Laparoscopy — no bile  1 (1%)  reaffirm that laparoscopic cholecystectomy in the elderly can
                                    leak/hematoma              be a challenging surgical undertaking. Thirty two (47%) patients
            Bile-leak and peritonism  Laparotomy, CBD  1 (1%)  had serious comorbidity with an ASA grade > III. Forty eight
                                    exploration and            (71%) had complex gallstone disease and 38 (56%) a complex
                                    extraction of stones       surgical dissection.
            Bile duct injuries      Laparoscopic repair  2 (3%)
                                                                  The high percentage of ASA grades > III is not unexpected
                                                               in our population and in keeping with previous octogenarian
            Table 5: Comparison of the timing of surgery and the difficulty of                             5,6
            dissection between cases converted to open surgery and those  populations undergoing laparoscopic cholecystectomy.  The
            completed laparoscopically                         associated comorbidities would account for the prolonged
                                                               median length of hospital stay of 3 (i.q. range 2-7) nights seen
                                  Converted  Laparoscopic  p-value
                                   (n = 5)   (n = 63)          in our patients. The ASA grade however did not show any
                                                               association with either conversion to open surgery or grade 2
            Timing of surgery
                                                               complications from surgery.
               Emergency             3         10       0.016
                                                                  The high incidence (71%) of complicated gallstone disease
               Elective              2         53
                                                               was consistent with the previous studies of laparoscopic
            Dissection                                         cholecystectomy in the elderly, 5,6,12  partly explaining a difficult
               Difficult dissection  5         33       0.039  dissection in 38 (54%) cases and in defining outcomes for these
               Straight forward      0         30              patients. In the group of patients requiring conversion to open
               dissection                                      surgery there was a significantly increased number of emergency
                                                               procedures (p = 0.016) and difficult dissections (p = 0.039) with
            Table 6: Comparison of the incidence of common bile duct stones  dense adhesions or scarring around the gallbladder and Calot’s
            between patients suffering grade 2 complications and those with  triangle. Difficult dissection is probably the commonest cause
            either grade 1 or no complications
                                                                            8
                                                               for conversion.  Whilst complicated gallstone disease should
                               Grade 2     Grade 1 or no  p-value  alert the surgeon to a potentially difficult dissection, even
                               complications  complications    patients reporting only biliary colic may have difficult
                               (n = 8)     (n = 60)
                                                               dissections, as in 9 of our cases.
            Common bile duct   8           20          0.0003     The grade of operating surgeon (consultant vs specialist
            stones
            No common bile     0           40                  registrar) starting the operation was not related to conversion
            duct stones                                        rates or grade 2 complications (p > 0.05). However almost half

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