Page 18 - World Journal of Laparoscopic Surgery
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Laparoscopic Cholecystectomy in Patients Over 80 Years is Feasible and Safe: Analysis of 68 Consecutive Cases

            or the preceding day. Emergency cases were defined as those  Table 1: Demographics of octogenarians (n = 68) undergoing
            where admission was for acute symptoms, which persisted or       laparoscopic cholecystectomy
            worsened indicating urgent surgical intervention.   Age; years*                            84 (80-96)
               Laparoscopic cholecystectomy was performed using a three  Sex; M : F                      31 : 37
            or four port technique. Cholangiography was performed  ASA grade;
            selectively. Common bile duct (CBD) stones were managed with  I II                           2 (3%)
                                                                                                         50 (%)
            either laparoscopic bile duct exploration or postoperative ERCP  > III                      32 (47%)
            according to the operating surgeon’s preference. The grade of  Complicated gallstone disease  48 (71%)
            the operating surgeon was noted. The duration of the procedure  Cholecystitis               23 (34%)
            was recorded from anesthetic charts.                   Common bile duct stones              28 (41%)
               Primary outcome measures were conversion to an open  Pancreatitis                         7 (10%)
            procedure and complications of surgery, including 30 days  Difficult dissection             38 (56%)
                                                                Timing of surgery
            mortality. Complications were recorded according to a previously  Elective                  55 (81%)
            described classification: 13                           Emergency                            13 (19%)
            • Grade 1: Minor complications treated with bedside therapy  Operating surgeon
              such as urinary retention.                           Consultant                           42 (62%)
            • Grade 2: Complications that require potentially morbid  Specialist registrar              14 (21%)
                                                                   Specialist registrar,
              interventions such as treatment of arrhythmias, surgery or  completed by consultant       12 (17%)
              other invasive procedure.
            • Grade 3: Complications that result in a residual disability such  *Mean
              as myocardial infarction or CVA.                      Table 2: Outcome measures for octogenarians (n = 68)
            • Grade 4: Death.                                            undergoing laparoscopic cholecystectomy
            Length of postoperative hospital stay was also recorded.  Duration of surgery; minutes*     90 (± 47)
                                                                Conversion to open surgery              05 (7.3%)
            Statistical analysis was performed using Chi-square test for  Complications                 16 (24%)
            categorical variables and t-test for continuous variables.  Grade 1                         08 (12%)
            Significance was accepted at a level < 0.05.          Grade 2                               08 (12%)
                                                                  Grade 3                               00
                                                                  Grade 4 (30 day mortality)            00
            RESULTS                                             Length hospital stay; postoperative nights §  03 (2-7)
            Sixty eight patients over 80 years [mean age of 84 years (range  *Mean and standard deviation
            80-96 years), 37 female] were identified as having undergone  § Median and interquartile range
            laparoscopic cholecystectomy as a primary procedure. This
            represented 0.03% of all laparoscopic cholecystectomies  Table 3: Reasons for conversion to open cholecystectomy
            performed during this period.                       Reasons for conversion             Number of cases
               Significant medical comorbidity was recorded in 32 (47%)  Gallbladder carcinoma           1
            patients with ASA > 3.                              Acute inflammation Calot’s triangle      2
               Forty-eight (71%) patients had complicated gallstone  Chronic inflammation/ scarring      2
            disease, 23 (34%) with cholecystitis, 28 (41%) with common bile
            duct stones and 7 (10%) with pancreatitis. Thirty-eight (56%)  The grade 1 complications were: three cases of acute urinary
            had a difficult dissection. Fifty-five (81%) of operations were  retention, one minor respiratory tract infection, one wound
            performed electively and 42 (62%) cases were performed by a  infection, one urinary tract infection, one intraoperative bleed
            consultant surgeon. Of the 26 cases started by specialist  not requiring transfusion and one case of surgical emphysema
            registrars, 12 had to be completed by consultants (Table 1).  complicating a difficult first port insertion. The grade 2
               The mean duration of surgery (excluding 1 case of a planned  complications necessitated transfusion or operative
            combined antireflux procedure) was 90 minutes (s.d. ± 47  intervention. One patient had laparoscopy and washout to
            minutes). Five (7.3%) operations were converted to open  investigate severe postoperative pain although no bile leak or
            surgery. The total number of patients having complications  perforation was identified. There were four cases of significant
            was 16 (24%), 8 (12%) being grade 1 and 8 (12%) grade 2. The  hemorrhage, two managed by transfusion and two requiring
            median length of hospital stay was 3 nights (interquartile range  laparotomy and washout. One case of bile leak was managed
            2-7). Outcome measures are summarized in Table 2. Reasons for  with laparotomy, CBD exploration and removal of CBD stones.
            conversion to open surgery are summarized in Table 3.  There were two (3%) cases of bile duct injuries, one presenting


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