Page 44 - Laparoscopic Surgery Online Journal
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Shyjus Puliyathinkal

          •  To reduce vascularization and blood loss, the myomas  TOTAL DURATION OF SURGERY (TABLE 2)
             were injected with diluted vasopressin.
                                                              In the study done by Franco Alessandri et al 2010 it was
          •  For subserous and intramural myomas, myomectomy
                                                              found that there was no significant difference in the operative
             was carried out the with a serosal incision vertically
                                                              time between group using barbed sutures and the group using
             over the convex surface of the myoma using a                       4
                                                              conventional sutures.
             monopolar hook.
                                                                 In another study done by JI Einarsson et al 2011, it was
          •  After exposure of the myoma pseudocapsule, grasping
                                                              found that use of bidirectional barbed suture was found to
             forceps were positioned to apply traction to the myoma
                                                              significantly shorten the mean (SD) duration of surgery
             and expose the cleavage plane.
                                                              [118 (53) minutes vs  162 (69) minutes; p < 0.05] when
          •  Enucleation was carried out by traction on the                                12
                                                              compared to conventional suturing.
             fibroid and by division with a unipolar hook or
                                                                 In a study conducted by JI Einarsson et al 2011 in animal
             mechanical cleavage.                             model it was found that the mean total procedure time was
          •  Hemostasis during dissection was achieved by bipolar        11
                                                              13.3 minutes.
             coagulation. Suturing was usually done along one or
                                                                 In yet another study done by Roberto Angioli et al
             two layers depending on the depth of incision with
                                                              2012 it was found that the mean operative time was
             barbed sutures or conventional vicryl sutures.
                                                              shorter in the V-Loc (51 ± 18.1 minutes) than in the control
          •  Removal of myoma:  Larger myoma were removed                           6
                                                              (58 ± 17.8 minutes) group.
             through posterior colpotomy. Medium and large size
             fibroid is morcellated using a morcellator or scissors.  INTRAOPERATIVE BLOOD LOSS
             For infected and suspected carcinoma, tissue retrieval
                                                              In the study done by Franco Alessandri et al 2010 it was
             bag should be used.
                                                              found that the intraoperative blood loss was significantly
          DISCUSSION                                          lower in group using barbed sutures than the group using
                                                              conventional sutures (p = 0.004). 4
          Time Required for Intracorporeal Suturing (Table 1)
                                                                 In another study done by JI Einarsson et al 2011 it was
          In the study done by Franco Alessandri et al 2010, it was  found that there were no significant differences with respect
          found that the time required to suture the uterine wall defect  to the intraoperative blood loss between barbed and
          was significantly lower in group using barbed sutures  conventional sutures. 12
          (11.5 ± 4.1 minutes) than in the group using conventional  In yet another study done by Roberto Angioli et al 2012
          sutures (17.4 ± 3.8 minutes; p < 0.001). 4          intraoperative bleeding was found to be significantly lower
             In the other study done on animal model by JI Einarsson  in the V-Loc group (p = 0.0076). 6
          et al 2011 myometrial closure was found to be significantly  In the study done by JI Einarsson et al 2010 in an animal
                                                                                                        11
          faster using barbed suture (126.5 seconds) when compared  model found that the mean blood loss was 159 ml.
          to traditional suture (272.6 seconds; p < 0.001). 12
                                                              FALL IN HEMOGLOBIN LEVELS
             In yet another study done by Roberto Angioli et al 2012
          it was found that suturing time was found to be significantly  In a study done by Roberto Angioli et al 2012, drop in
          lower in the V-Loc (Barbed suture) than in the control  hemoglobin was found to be significantly lower in the
          (9.9 ± 4.3 vs 15.8 ± 4.7 minutes; p = 0.0004) group. 6  V-Loc group (p = 0.0176). 6


                                          Table 1: Time needed for intracorporeal suturing
                Study                          Barbed sutures         Conventional sutures      p-value
                Franco Alessandri et al 2010   11.5 ± 4.1 mins        17.4 ± 3.8 mins           <0.001
                JI Einarsson et al 2011        126.5 seconds          272.6 seconds             <0.001
                Roberto Angioli et al 2012     9.9 ± 4.3 mins         15.8 ± 4.7 mins           = 0.0004



                                                Table 2: Total duration of surgery
                Study                       Barbed sutures     Conventional sutures    p-value
                Franco Alessandri et al 2010                                           No significance difference
                JI Einarsson et al 2011     118 minutes        162 minutes             <0.05
                Roberto Angioli et al 2012  51 ± 18.1 mins     58 ± 17.8 mins          NA

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