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REVIEW ARTICLE
            Laparoscopic Ventral Hernia Repair with Polypropylene

            Mesh: A Literature Review


            Elmutaz Kanani


             AbstrAct
             Background: Laparoscopic ventral hernia repair (LVHR) is currently considered the gold standard. However, the mesh selection is still
             controversial. The aim of this review is to look for evidence that supports the use of polypropylene mesh (PPM) in the intraperitoneal position in
             LVHR.
             Materials and methods: The literature was searched systematically using Google Scholar and PubMed for controlled studies, prospective
             descriptive series, and retrospective case series.
             Results: A total of 11 studies were retrieved. All the studies were either retrospective or animal experiments. Their outcomes are heterogeneous
             and they have multiple weaknesses.
             Conclusion: The literature clearly lacks data from controlled randomized trials in humans that can give strong evidence. The use of intraperitoneal
             PPM in LVHR remains an individual surgeon preference decision until well-designed prospective double-blind randomized controlled clinical
             trials are available.
             Keywords: Complication, Laparoscopy, Mesh, Polypropylene, Prolene, Ventral hernia.
             World Journal of Laparoscopic Surgery (2020): 10.5005/jp-journals-10033-1394


            IntroductIon                                       General Surgery Department, Khoula Hospital, Muscat, Oman

            In laparoscopic ventral hernia repair (LVHR), there are different   Corresponding Author: Elmutaz Kanani, General Surgery Department,
            techniques practiced like three ports repair, two ports   Khoula Hospital, Muscat, Oman, Phone:  +968 99533569, e-mail:
            repair, intraperitoneal, and totally extraperitoneal repair. The   mutazkanani313@hotmail.com
            intraperitoneal technique (IPOM), although simple and successful,   How to cite this article: Kanani E. Laparoscopic Ventral Hernia Repair
            faces the dilemma of mesh selection. A large number of variable   with  Polypropylene  Mesh:  A  Literature  Review.  World  J  Lap  Surg
            mesh types are available in the market and each claimed to be   2020;13(1):31–34.
            superior to others. Likewise, the cost is not uniform as some are very   Source of support: Nil

            expensive while others are cheaper. Reliable data on mesh safety   Conflict of interest: None
                                              1
            and efficacy are not available to the clinician.  The polypropylene
            mesh (PPM) is among the cheapest and had stood the test of time   They were four literature reviews, four case series, and three
            in extraperitoneal hernia repair. Its use in intraperitoneal position   animal experiments. The articles were then analyzed in terms of
            still remains doubtful due to the possibility of its adhesion to   year of publication, type of study, details of the study, number of
            bowel causing serious complications like intestinal obstruction   participant subjects, duration of the study and maximum duration
            and fistulization. Newly developed meshes proved to reduce   of follow-up, method of assessment of complications, and the final
            the inflammatory response and therefore reduce the adhesion   recommendations.
                    2
            formation.  Coatings added to newer meshes aim also to prevent
            bowel adhesion to the mesh surface. In fact, this also had been   results
            scrutinized and some newer meshes were found to cause adhesions
                              3
            in animal experiments.  This conflicting information put the   A total of eleven articles were retrieved. Three were animal
            surgeon in a difficult situation especially when expensive types of   experiments, four are case series, and four are literature reviews.
            mesh cannot be provided because of financial restrictions. Patient   Four studies concluded that PPM is safe however; none of them was
            safety should not be simply jeopardized because of financial   a prospective randomized study. On the other hand, four studies
            aspects and this is a major ethical issue.         gave recommendations against the PPM. The remaining three
               In this review, we tried to answer the question of is it safe to   studies either left the choice of mesh to the surgeon’s preference
            use intraperitoneal PPM in ventral hernia repair by retrieving the   or recommended a barrier between mesh and intestine. The
            evidence from the published literature about the topic.  case series have in common limited number of subjects and they
                                                               vary in follow-up duration as all had short-term follow-up. The

            MAterIAls And Methods                              assessment methods were also different between the studies. The
                                                               results of animal experiments cannot be generalized to humans.
            A systematic literature search using the databases of Google   The literature review recommendations are heterogeneous and
            Scholar and PubMed was performed. Eleven articles were retrieved.   nonconclusive. Table 1 summarizes the findings of all these articles.



            © The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.
            org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to
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