Page 34 - World Journal of Laparoscopic Surgery
P. 34

Sameer AlOsaimi et al
          diSCuSSiOn                                          for CP. Pelvic adhesions following previous pelvic opera-
                                                              tion or infection also contribute to a high incidence of
          The CP may occur as a result of direct mechanical pene-              9,18
          tration with the instrument tip, sharp flexion of the   sigmoid perforation.   Some authors have also suggested
          colonoscope over distended bowel or due to thermal or   that patients with multiple comorbidities are at greater
                                                                              16,19
          electrical injury during therapeutic intervention, such   risk of perforation.   Furthermore, that advanced age of
          as polypectomy.                                     patients and endoscopy performed by a trainee shown to
                                                                                 16,20
                           15
             Anderson et al  discussed the risks of perforation   increase the risk of CP.   It was found that mechanical
          after either sigmoidoscopy or colonoscopy. The study   stress is the most common mechanism of perforation,
          compared 10486 colonoscopies with 49501 sigmoido-   the other perforations were associated with cone biopsy,
          scopies done over 10 years (1987-1996) at Mayo Clinic,   electrocautery and pneumatic causes. 21
                                                                                            13,14
          they found two deaths secondary to perforation from      Similar to the first reported case,   we think scoliosis
          colonoscopy, corresponding to an overall mortality rate   with sever skeletal deformity can interfere with the usual
          after a colonoscopy of 0.02% and an incidence of death   path of introducing the colonoscope, thus causing CP.
          after a perforation of 10%.                            Colonoscopic perforations may be managed opera-
                      16
             Gatto et al  explored a large population-based data-  tively or nonoperatively. Several large series have
          base to compare the incidence of perforation asso ciated   reported that many patients with perforations may be
          with both of these flexible endoscopic procedures and   treated successfully without operations. Conservative
          to investigate what factors predict the occurrence of this   treatment includes bowel rest, intravenous fluids, and
          complication, they found that the risk of perforation    antibiotics to allow the perforation to seal. 15,22-25
          after colonoscopy was statistically significantly increased      In Korean study, it is reported that 36% of the patients
          among patients with diverticulosis and obstruction,   were managed conservatively. Nine patients under-
          whereas the risk of perforation after sigmoidoscopy was   went endoscopic perforation closure using hemoclips.
          increased among patients with diverticulosis and abdo-  Twenty-nine percent of those patients underwent colonic
          minal pain. In their study, there were 77 perforations after   resection with anastomosis. In a retrospective review
          39286 colonoscopies and 31 perforations after 35298 sig-  of laparoscopic repair of colonic perforations, the mean
          moidoscopies procedures. Further more, risk of CP from  colonic perforation size was 2.7 cm. 26
          either procedure increased in association with increasing     Operative treatment is most often necessary in
          age and the presence of two or more comorbidities.  patients with generalized peritonitis, large injuries, or
                            17
             Lohsiriwat  et  al   prospectively  reviewed  10124  failed conservative treatment. 27
          patients undergoing either colonoscopy or flexible sig-     In our case, the perforation located at the anterior
          moidoscopy between January 2005 and July 2008. Over  wall of sigmoid colon, the patient was in peritonitis, with
          a 3.5-year period, there were 15 colonic perforations,  radiological evidence of viscus perforation, so surgical
          they found that patient gender, emergency endoscopy,  intervention was required. As she was hemodynamically
          anesthetic method, and the specialty or experience of  stable, we chose diagnostic laparoscopy to diagnose and
          the endoscopist were not significantly predictive of CP  proceed with surgical management.
          rate. In the other hand, patient age of over 75 years and     The specific operative procedures used will depend
          therapeutic colonoscopy were two important risk factors  on the size of perforation, the degree of peritoneal soilage,
























               Fig. 1: Chest X-ray showing air under the diaphragm  Fig. 2: Abdominal X-ray showed severe scoliotic deformity of
                                                                   the lumbar spine with massive pneumoperitoneum
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