This video demonstrate Optimal Position of Ports in Laparoscopy - Lecture by Dr R K Mishra. We investigated the optimal position of the optical port of laparoscope in relationship to the working ports. The manipulation angle, defined as the angle formed by the line of action determined by the two working ports and the azimuth angle line of vision determined by the laparoscope, was varied by 30 degrees intervals from 0 degree to 180 degrees to the left and to the right. We also studied the time taken to accomplish a standardized task of tying a square knot with each optical angle in a laparoscopic simulator setting. The optimal range of the manipulation angle is 60 degrees and azimuth angle is 30 degree to left and 30 degrees to the right of the optimal position of 0 degree.