This Video demonstrate Mishra's Knot (An Ideal Extra Corporeal Knot used in Laparoscopic Surgery). Mishra's Knot are useful when the intracorporeal space is insufficient for the instrument tips to maneuver or if the surgeon lacks intracorporeal knotting skills. Mishra's Knot work best with slippery monofilament suture materials. A common misconception exists about extracorporeal Mishra's Knot and that is that it requires less skill to tie than intracorporeal knots. On the contrary, to tie extracorporeal knots safely considerable skill and understanding of tissue texture are required. Knots tied with braided suture material have a tendency to lock up to soon, outside the desired location. Pre-tied Mishra's Knot available commercially generally use Mishra's Knot and after one ligature has been made, this product can be used again by preparing another loop that is secured with the Mishra's Knot.