This video demonstrate Total Laparoscopic Hysterectomy with ligation of Uterine Artery by Dr. R K Mishra at World Laparoscopy Hospital. In this surgery for ligation of uterine artery Mishra's knot is used and for the vault closure Weson knot is used. The patient was suffering from severe DUB and surgical removal of the uterus can be lifesaving for those suffering from gynecological cancers or the severe pain and heavy bleeding due to fibroids or endometriosis. Today, there are several surgical approaches that are far less invasive than a total abdominal hysterectomy, which is still widely performed. The total laparoscopic hysterectomy (TLH) offers women an option that is far less invasive than other surgical approaches. The need for a hysterectomy is an important and difficult decision.