This video demonstrate Laparoscopic Myomectomy for Large Intramural Fibroid Uterus. Despite the increased operation time and blood loss, laparoscopic myomectomy can be safely performed in the treatment of large uterine fibroid. However, high risk of blood transfusion in these patients has to be kept in mind. With laparoscopic approach, there is minimal tissue handling which reduces risk of adhesions. Saline irrigation is also constantly in use which prevents drying of tissues and blood clots from sticking to the tissues. Meticulous control of bleeding also is essential. Finally, adhesion prevention barrier such as Adept solution or Interceed is used at the end of the procedure.