Total Laparoscopic Hysterectomy is currently accepted as a safe, efficient way to manage benign uterine pathology by doctors and patients and is an acceptable alternative to standard abdominal hysterectomy/ In recent days with the popularization and advance of the Total Laparoscopic Hysterectomy, scholars are increasingly exploring and expanding their surgical scope of application. In the past, a large uterus with uterus size above 12 weeks of gestation was considered as the contraindication for laparoscopic hysterectomy due to limited visibility and access to uterine vascular associated with the high risk of complications such as hemorrhage, bowel and urinary injury, difficulty in extracting the uterus, and extended duration of the procedure and was more suitable for laparotomy. With the expansion of the surgical indications of the laparoscopic hysterectomy, there have been a number of publications reporting the Total Laparoscopic Hysterectomy for large uterus.