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          Balachandran Premkumar, Subhankar Paul                                10.5005/jp-journals-10033-1318
          RevieW ARticLe


          Achalasia Cardia: Revisited

          1 Balachandran Premkumar,  Subhankar Paul
                                  2

          ABSTRACT

          Introduction: Achalasia cardia is a very common esophageal
          motility disorder affecting a large population worldwide including
          the Indian subcontinent. The diagnosis of the condition is equally
          important as the treatment ranges from medicines to botulinum
          injection, to pneumatic dilatation and surgery. This study gives
          an overview of achalasia cardia and the modalities to diagnose
          and treat the condition.
          Keywords: Achalasia cardiae, Cardiospasm, Esophageal
          achalasia, Esophageal peristalsis.

          How to cite this article: Premkumar B, Paul S. Achalasia
          Cardia: Revisited. World J Lap Surg 2017;10(3):112-116.
                                                                         Fig. 1: Lower esophageal sphincter
          Source of support: Nil
          Conflict of interest: None
                                                              DIFFERENTIAL DIAGNOSIS

          INTRODUCTION                                        A few other conditions may mimic the symptoms of
                                                                            7
                                                              achalasia cardia,  such as
          Achalasia cardia is an esophageal motility disorder in   •  Gastroesophageal reflux disease (GERD),
          which the smooth muscle layer of the esophagus loses   •  Hiatus hernia, and
          normal peristalsis and the lower esophageal sphincter   •  Psychosomatic disorders.
          (LES) fails to relax properly in response to swallowing
          (Fig. 1). 1-3                                       INVESTIGATIONS

                                                              Specific tests for achalasia are barium swallow and
          SYMPTOMS
                                                              esophageal manometry. In addition, endoscopy, with or
          The main symptoms of achalasia are dysphagia (difficulty   without endoscopic ultrasound, may be done to rule out
                                                           4
          in swallowing) and regurgitation of undigested food.    the possibility of cancer. 4
          Dysphagia tends to become progressively worse over
          time to involve both fluids and solids. Some achalasia  Barium Swallow
          patients also experience weight loss, coughing when   The classical “Bird’s beak” or “Rat’s tail” appearance may
          lying in a horizontal position, and chest pain which may   be seen. An air-fluid margin is often seen over the barium
          be perceived as heart burn. The chest pain experienced,   column due to the lack of peristalsis. 8
          also known as cardiospasm and noncardiac chest pain    A 5-minute timed barium swallow can provide a
                                                     5
          (NCCP), can often be mistaken for a heart attack.  It can   useful benchmark to measure the effectiveness of treat-
          be very painful in some sufferers. The food and liquid,   ment.  It also shows aperistaltic contractions, increased
                                                                   9
          including saliva, are retained in the esophagus and may   intraesophageal pressure, and failure of relaxation of the
          cause aspiration. 6
                                                              LES (Fig. 2). 10


                     2
           1 Consultant,  Registrar                           Esophageal Manometry
           1,2 Department of General Surgery, Apollo Hospitals, Chennai   Because of its sensitivity, manometry is considered the
           Tamil Nadu, India                                  key test for establishing the diagnosis.  Manometry
                                                                                                  11
           Corresponding Author: Balachandran Premkumar, Consultant   reveals failure of the LES to relax with swallowing and
           Department of General Surgery, Apollo Hospitals, Chennai, Tamil   lack of functional peristalsis in the smooth muscle of
           Nadu, India, e-mail: drbpk@hotmail.com
                                                              esophagus (Graph 1). 12


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