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Difficult Laparoscopic Cholecystectomy
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            which were discussed earlier. In our study, we had no conversions   et al.,  Corr et al.,  Lein and Huang,  and Kama et al.  have reported
            to open cholecystectomy. All 100 patients have had a standard   in their studies that there is an appreciable interconnection in
            laparoscopic cholecystectomy.                      anticipating a difficult laparoscopic cholecystectomy if the stone in
               In this study, we had a remarkable association with the thickness   the GB measures more than or equal to 1 cm in diameter. Chindarkar
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            of the GB wall. A total of 36 patients had an increased breadth. When   et al.  reported 40.0% of sensitivity, specificity of 92.5%, 72.7% of
            we had a breadth of more than 4 mm, 27 (75%) of them had a difficult   PPV, NPV of 75.5%, and 75% accuracy with p = 0.004. Our study
            laparoscopic cholecystectomy and the rest 9 (25%) had an easy   had a 52.5% of sensitivity, specificity of 76.7%, and PPV of 60.0%,
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            laparoscopic cholecystectomy. Daradkeh et al.,  Lal et al.,  Carmody   NPV of 70.8%, and 61% accuracy with p = 0.003 for the criterion if
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            et al.,  Kreimer et al.,  and Corr et al.  also reported in their respective   GB calculus measurement in length is more than or equal to 1 cm.
            studies that the GB wall thickness was the best ultrasonic parameter   Other two criterion in preoperative ultrasound, namely, the
            to predict a difficult laparoscopic cholecystectomy.  size of distension of the GB of more than or equal to 5 cm and the
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               Chindarkar et al.  and Dinkel et al.  reported the sensitivity of   CBD caliber size of more than or equal to 6 mm was found to have
            65 and 66.7%, specificity of 97 and 94.1%, positive predictive value   no statistical significance in predicting a difficult laparoscopic
            (PPV) of 92.9 and 84.2%, negative predictive value (NPV) of 84.8, and   cholecystectomy. This is a contrast discovery we found to the study
            85.3% for escalating in the breadth of the wall of the GB of more than   made by Chindarkar et al., Lal et al., Corr et al., and Daradkeh et al.
            4 mm as a criterion for operative difficulty. Whereas in this study, we   They have published that they noticed a moderate interrelation in
            had a sensitivity of 67.5%, specificity of 85.0%, PPV of 75.0%, NPV   anticipating a difficult laparoscopic cholecystectomy.
            of 79.7%, and an accuracy of 78.0% for escalating in the breadth of   Several studies have attempted to form a scoring to predict a
            the wall of the GB of greater than 4 mm as a criterion to anticipate a   difficult laparoscopic cholecystectomy preoperatively. However,
            difficult laparoscopic cholecystectomy, respectively, with p = 0.000.  most of these studies are complex and use large number of
               Next to increased thickness, the further notable statistically   determining factors. These studies are difficult to adapt and use in
            significant criterion was the GB stone impacted at the neck. Out of   regular day-to-day practice. 22–25  In our studies, the scoring method
            20 cases that had stone impacted and adhered at the GB neck, 15   was made in such a way that it is easy to follow and to use on
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            cases were found to be difficult. Daradkeh et al.,  Santambrogio   regular day-to-day practice. In the study reported by Chindarkar
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            et al.,  and Randhawa and Pujahari  have reported that when we   et al., they had a 92.86% of sensitivity, 97.5% of specificity, PPV of
            had a case where the stone is firmly attached to the neck of the GB   65.0%, NPV of 97.5%, and accuracy of 86.66% for the preoperative
            there are more chances that the case will be having a difficulty in   ultrasound score of more than or equal to 4. Whereas in this study,
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            dissection during surgery. Chindarkar et al.  and Akhter et al.  have   the sensitivity was 100.0%, specificity was 71.43%, PPV of 40.0%,
            reported that there is a firm association with the impaction of the   NPV of 100.0%, and 76.0% accuracy for preoperative ultrasound
            stone at the neck of the GB to anticipate a difficult laparoscopic   scores more than or equal to 4 as a criterion to predict a difficult
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            cholecystectomy. Chindarkar et al.  reported a sensitivity of 40%,   laparoscopic cholecystectomy with p = 0.000.
            specificity of 100%, PPV of 100%, NPV of 76.9%, and 80% accuracy   The difficulties we faced in our study intraoperatively are the
            for the stone impaction at the GB neck.            presence of dense peri GB adhesions and frozen Calot’s triangle.
               The chief difficulty observed during the surgery is when the   There was a minimal tear in the GB during dissection which
            calculi get adhered to the neck and making it difficult to hold and   accounted for bile and stone spillage. In our study, there was no injury
            grasp with laparoscopic instruments. It slows down and restricts   made to the hepatic duct, CBD, and hepatic artery. We did not have
            retraction and the dissection of the Calot’s triangle. There is also   bleeding that hindered the visual field, buried or intrahepatic GB.
            mucocele formation due to mucus collection with in turn makes the   In this study, there were no conversions to open cholecystectomy.
            GB to be distended and tense. In our study, we found a sensitivity   All 100 patients have had a standard laparoscopic cholecystectomy.
            of 37.5%, specificity of 91.7%, PPV of 75.0%, NPV of 68.8%, and 67%   Our observation made from the study agrees with other studies by
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            accuracy with p = 0.000.                           Corr et al.,  Fried et al.,  Chindarkar et al.,  Santambrogio et al.,
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               Our study also discovered that there is an appreciable   and Daradkeh et al.,  that the preoperative ultrasonography finding
            interconnection between the existence of pericholecystic collection   can help in predicting a difficult laparoscopic cholecystectomy.
            in anticipating a difficult laparoscopic cholecystectomy. In our study,
            out of 100 patients, 39 of them had the presence of pericholecystic  conclusIon
            fluid collection in their preoperative ultrasound. Among those 39   Overall critical complication rates seen in a standard laparoscopic
            of them, 23 patients had a difficult laparoscopic cholecystectomy.   cholecystectomy are more and seen frequently when compared
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            In the study done by Chindarkar et al.  and Nidoni et al.,  they   to traditional open cholecystectomy. Most of these complications
            have reported that presence of pericholecystic collection have a   are made due to the difficulty faced during the surgery. Therefore,
            significant correlation with a difficult laparoscopic cholecystectomy.   it would be helpful to have some tools to recognize a difficult
            They also reported a sensitivity of 50.0 and 70%, specificity of 97.5   laparoscopic cholecystectomy preoperatively. Determining the
            and 91.76%, PPV of 90.9 and 33.33%, NPV of 79.6 and 98.11%, and   factors that can predict a difficult laparoscopic cholecystectomy
            accuracy of 81.7 and 73.33%, respectively. In our study, we had a   preoperatively based on ultrasound findings was the aim of our study.
            result of 57.5% of sensitivity, specificity of 73.3%, PPV of 59.0%, NPV   The primary objective of our study is to validate a cut-off score from
            of 72.1%, and accuracy of 67% with the p = 0.002.  the ultrasonography formulated scoring method in identifying a
               Few studies have reported that there is a statistical significance   difficult laparoscopic cholecystectomy. Finding the most notable and
            between the sizes of the GB calculus with the difficult laparoscopy   remarkable criterion in ultrasonography which is interrelated with a
            cholecystectomy. In this study, 35 patients had their calculus size   difficult laparoscopic cholecystectomy was our secondary objective.
            more than or equal to 1 cm. Among those 35 patients, 21 patients   A total of 100 patients who are satisfied to our inclusion criteria
            (60%) had a difficult laparoscopic cholecystectomy. Chindarkar   who were admitted for laparoscopic cholecystectomy were included
            232   World Journal of Laparoscopic Surgery, Volume 15 Issue 3 (September–December 2022)
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