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Role of Laparoscopy in Abdominal Tuberculosis Diagnosis























            Figs 2A and B: Intraoperative findings. (A) Mesenteric lymph node biopsy; (B) Parietal wall tubercles


                              Table 1: Comparison of various methods for the diagnosis of TB with a visual impression
                                           Visual findings        AFB                     Gene
                               Study group    S/o TB   AFB staining culture  Histopathology  TB PCR  Xpert
                               50              42         20       28       38       38    39
                               Percentage      84         40       56       76       76    78


                                      Table 2: Sensitivity and specificity test
                                      Visual impression  Disease       No disease  Total
                                      Positive       True-positive (39)  False-positive (3)  42
                                      Negative       False-negative (0)  True-negative (8)  8
                                                          39             11        50


                              Table 3: Comparison of all tests with laparoscopy
                                                                   Positive predictive  Negative predictive
                                            Sensitivity (%)  Specificity (%)  value (%)  value (%)
                              AFB staining     51.28       100          100          36.66
                              AFB culture      59.57       100          100          36.66
                              Histopathology    97.4       100          100          91.66
                              TB PCR            97.4       100          100          91.60
                              Gene Xpert        100        100          100           100
                              Laparoscopy       100         72         92.85          100



               In the last few years, laparoscopy has emerged as a safe and   AFB staining is positive in 40% of subjects. The sensitivity and
            rapid investigation for the direct visualization of the peritoneal   specificity were 51.28 and 100%, respectively. The positive predictive
            cavity in cases of suspected abdominal Kochs. Laparoscopy   value was 100%, and the negative predictive value was 91.66%.
            under general anesthesia permits the observation of the entire   AFB culture is positive in 56% of subjects. The sensitivity
            peritoneal space and provides tissue samples in targeted areas   and specificity were 59.57 and 100%, respectively. The positive
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            for histopathology.  Few complications during laparoscopy are   predictive value was 100%, and the negative predictive value was
            reported without any mortality. Thus, laparoscopy can be safely   36.66%.
            performed in all patients suspected to have abdominal TB for rapid   Histopathology is a very specific method for the diagnosis of
            diagnosis rather than relying on conventional methods that may   abdominal TB. In our study, (38/50) 78% of the patients who were
            take up to 4–6 weeks.                              diagnosed to have TB had histopathology findings suggestive of TB.
               In our study, we have made an attempt to find the efficacy of   The association was statistically significant (p <0.05). The sensitivity
            diagnostic laparoscopy in abdominal TB. We have compared visual   of the test was 97.4%, and the specificity was 100%. The positive
            impression during laparoscopy with different tests like AFB stain,   predictive value was 100%, and the negative predictive value was
            AFB culture, histopathology, TB PCR, and Gene Xpert.  91.66%.

                                                 World Journal of Laparoscopic Surgery, Volume 14 Issue 3 (September–December 2021)  147
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