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                                 Short- and Long-term Effects of LSG on Body Weight and Glucose Homeostasis in Diabetic Patients
          postoperative (240.3 ± 30.9) mg/dL (p < 0.001) compared  REFERENCES
          with the baseline (280.7 ± 45.4) mg/dL independent     1.  Singh RB, Pella D, Mechirova V, Kartikey K, Demeester F,
          from the weight loss. At 3, 6, 9 months after surgery,   Tomar RS, Beegom R, Mehta AS, Gupta SB, De Amit K, et al.
          a significant declining in PPBG, p < 0.001, occurred    Prevalence of obesity, physical inactivity and undernutrition,
          but it was associated with significant reduction of     a triple burden of diseases during transition in a develop-
          BMI. After 12 months, a significant reduction of BMI    ing economy. The Five City Study Group. Acta Cardiol 2007
                                                                  Apr;62(2):119-127.
          occurred (p < 0.001) with nonsignificant decline in the     2.  Rosenthal R, Li X, Samuel S, Martinez P, Zheng C. Effect of
          PPBG level. (By researching we did not find a published   sleeve gastrectomy on patients with diabetes mellitus. Surg
          data about PPBG levels after SG for comparing with      Obes Relat Dis 2009 Jul-Aug;5(4):429-434.
          our results.)                                         3.  Sugerman HJ, Starkey JV, Birkenhauer. A randomized
                                                                  prospective trial of gastric bypass versus vertical banded
          CONCLUSION                                              gastroplasty for morbid obesity and their effects on sweets
                                                                  versus non-sweets eaters. Ann Surg 1987 Jun;205(6):613-624.
          Surgical procedure of LSG resulted in marked weight     4.  Korkeila M, Kaprio J, Rissanen A, Koskenvuo M. Consistency
          loss, BMI, improved glucose homeostasis, and remission   and change of body mass index and weight. A study on 5967
          of T2DM. Our study has found that LSG is an effective   adult Finnish twin pairs. Int J Obes Relat Metab Disord 1995
                                                                  May;19(5):310-317.
          surgical treatment for most severely or morbidly obese     5.  Lagacé M, Marceau P, Marceau S, Hould FS, Potvin M,
          patients with DM. Weight loss is an effective treatment for   Bourque RA, Biron S. Biliopancreatic diversion with a new
          patients with these medical problems. Our results open   type of gastrectomy: some previous conclusions revisited.
          the gate for MS in patients with normal BMI to control MS   Obes Surg 1995 Nov;5(4):411-418.
          different components, such as cardiac events, polycystic     6.  Ren CJ, Patterson E, Gagner M. Early results of laparoscopic
          ovary syndrome. The SG is associated with a high rate of   biliopancreatic diversion with duodenal switch: a case series
                                                                  of 40 consecutive patients. Obes Surg 2000 Dec;10(6):514-523.
          resolution of T2DM at 12 months after surgery in severely     7.  Payne JH, DeWind L, Schwab CE, Kern WH. Surgical treat-
          obese patients with T2DM. The rate of T2DM resolution   ment of morbid obesity. Sixteen years of experience. Arch
          in patients undergoing SG in our study is similar to that   Surg 1973 Apr;106(4):432-437.
          reported in previous case series following this surgical     8.  Türkoglu C, Duman BS, Günay D, Cagatay P, Ozcan R,
          technique.                                              Büyükdevrim AS. Effect of abdominal obesity on insulin
                                                                  resistance and the components of the metabolic syndrome:
                                                                  evidence supporting obesity as the central feature. Obes Surg
          SUMMARY                                                 2003 Oct;13(5):699-705.
          Bariatric surgery is known to be a highly effective and     9.  Steinbrook R. Surgery for severe obesity. N Engl J Med 2004
                                                                  Mar;350(11):1075-1079.
          long-lasting treatment for morbid obesity and many     10.  Schauer PR, Burguera B, Ikramuddin S, Cottam D, Gourash W,
          related conditions, including T2DM and MS.              Hamad G, Eid GM, Mattar S, Ramanathan R, Barinas-Mitchel E,
             Laparoscopic sleeve gastrectomy is emerging as a new   et al. Effect of laparoscopic Roux-en Y gastric bypass on type
          promising therapy for the treatment of morbid obesity.   2 diabetes mellitus. Ann Surg 2003 Oct;238(4):467-484.
          This procedure, originally conceived as a first stage for     11.  Pasquali R, Vicennati V, Scopinaro N, Marinari G, Simonelli A,
          achieving weight loss in superobese patients before per-  Flamia R, Casimirri F, Gagliardi L. Achievement of near-
          forming GBP or BPD, has revealed to be effective on its   normal body weight as the prerequisite to normalize sex
                                                                  hormone-binding globulin concentrations in massively obese
          own and a potential competitor with these operations.   men. Int J Obes Relat Metab Disord 1997 Jan;21(1):1-5.
          Laparoscopic sleeve gastrectomy is a feasible and safe     12.  Dixon JB, O’Brien PE, Playfair J, Chapman L, Schachter LM,
          bariatric surgery procedure for morbid obesity, although   Skinner S, Proietto J, Bailey M, Anderson M. Adjustable
          evaluation of long-term outcome will be necessary to    gastric banding and conventional therapy for type 2 diabetes:
          determine whether it yields durable results. Few studies   a randomized controlled trial. JAMA 2008 Jan;299(3):316-323.
          have examined the effects of LSG on glucose control     13.  Gan SS, Talbot ML, Jorgensen JO. Efficacy of surgery in the
                                                                  management of obesity-related type 2 diabetes mellitus. ANZ
          and comorbidities in obese T2DM patients, and limited   J Surg 2007 Nov;77(11):958-962.
          information is available on the long-term efficacy of this     14.  Vidal J, Ibarzabal A, Romero F, Delgado S, Momblán D,
          procedure. Our study showed that the LSG is effective to   Flores L, Lacy A. Type 2 diabetes mellitus and the metabolic
          achieve weight loss and resolve T2DM, and the resolution   syndrome following sleeve gastrectomy in severely obese
                                                                  subjects. Obes Surg 2008 Sep;18(9):1077-1082.
          T2DM in this study was better in comparison with the     15.  Peterli R, Wölnerhanssen B, Peters T, Devaux N, Kern B,
          results of other studies, so this study evaluated the short   Christoffel-Courtin C, Drewe J, von Flüe M, Beglinger C.
          and long-term effects (1 day, 3, 6, 9, and 12 months) of   Improvement in glucose metabolism after bariatric surgery:
          LSG on body weight and glucose homeostasis in morbid    comparison of laparoscopic Roux-en-Y gastric bypass and
          obese T2DM subjects not adequately controlled with      laparoscopic sleeve gastrectomy: a prospective randomized
          medical therapy.                                        trial. Ann Surg 2009 Aug;250(2):234-241.
          World Journal of Laparoscopic Surgery, May-August 2017;10(2):45-50                                49
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