This video demonstrates Total Laparoscopic Hysterectomy with infrared fluorescence imaging of Ureter and Uterine artery with ICG at World Laparoscopy Hospital by Dr. R.K. Mishra. Injecting indocyanine green (ICG) enables the operators to identify the ureter and the uterine artery to perform a safe laparoscopic hysterectomy. A cyanine vital dye indocyanine green (ICG) is a safe NIR fluorophore emitting 800~840 nm of light and has been used in numerous surgical procedures. It also allows them to decide on the extent of the dissection and validate the completeness of the dissection. In this video, a laparoscopic near-infrared fluorescent camera was used, showing the fluorescent signal in diverse modes. According to the increasing needs and interest in precision surgery, which is characterized by individual tailored surgical strategies, image-guided surgery is receiving increased attention as the most intuitive and strong methodology to implement precision surgery.