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REVIEW ARTICLE
            Natural Orifice Specimen Extraction: An Incisionless

            Approach for Colorectal Cancer (Technical Report)


            Islam H Metwally


             AbstrAct
             Background: Natural orifice surgery represents a greatstep to the future. Difficulties arose on our current practice. Reviewing the literature
             does not solve all the debates.
             Report: The author suggests a simple algorithm for transanal natural orifice specimen extraction (NOSE).
             Conclusion: Transanal extraction of colectomy and/or proctectomy specimen is a readdily feasible technique.
             Keywords: Colon, Natural orifice, Rectum, Specimen extraction, Transanal.
             World Journal of Laparoscopic Surgery (2018): 10.5005/jp-journals-10033-1351



            bAckground                                           Department of Surgical Oncology, Oncology Center Mansoura
            Natural orifice specimen extraction (NOSE) for colon and rectal   University, Mansoura, Dakahlia, Egypt
            cancer is still taking its first steps in oncology practice. Several safety   Corresponding Author: Islam H Metwally, Department of Surgical
            questions, as well as, technical difficulties arose with practizing   Oncology, Oncology Center Mansoura University, Mansoura,
                       1
            this technique.   As a part of Oncology Center Mansoura University   Dakahlia, Egypt, Phone: +20 1002985865, e-mail: drislamhany@mans.
            (OCMU) center current clinical trial on natural orifice transluminal   edu.eg
            endoscopic surgery (NOTES) for colorectal cancer with ClinicalTrials.  How to cite this article: Metwally IH. Natural Orifice Specimen
            gov Identifier: NCT02549456, transanal NOSE is practiced. Different   Extraction: An Incisionless Approach for Colorectal Cancer (Technical
            technical steps in our practice, as well as, in published series are   Report). World J Lap Surg 2018;11(3):147–148.


            displayed in an algorithm with videos when possible.  Source of support: Nil

                                                               Conflict of interest: None
            technique
            Excluding cases of intersphincteric resection and some cases   B2: If you are planning for a side-to-end anastomosis, then do
            of ultralow anterior resection where specimen extraction is   colotomy and insert the anvil with its auxiliary trocar and push
            straight forward and anastomosis is done on the anal verge,   against wall to make a new narrow colotomy (with/without
            the classic transanal NOSE technique is depicted in Flowchart 1    purse string reinforcement), or use a guide tube to facilitate
            and below:                                            the anvil exteriorization.
                                                                                     2
            Step I: Laparoscopic sigmoidectomy, anterior, low, or ultralow   B3: If you are planning for a pouch reconstruction, then do the
            resection is done.                                    pouch with a linear stapler, then insert the anvil through the
            Step II: Cut the distal end by advanced bipolar for the mesentry or   resultant opening.
                                                                                3
            mesorectum, then use scissors to cut the lumen (to avoid sealing   Step IV: Only applies for technique IIIB, extract the specimen either
            of the wall that may hinder specimen extraction).  by an Endobag® (Covidien, MA, USA) (Video 3), or a camera sleeve,
                                                                                                                4
            Step III: Either.
                                                                        5
                                                               or aCai tube,   or a rigid platform; transanal endoscopic microsurgery
            •  A: Use a long instrument to grip the colon and retrieve it through   (TEM) (Richard Wolf, IL, USA) or transanal endoscopic operation (TEO)
              the anal canal. Cut the proximal end and insert the anvil extra-  (Karl Storz, Tuttilingen, Germany).
              corporeal (preferred method if feasible). Here you can close the   Step V: Close the distal stump (as in step IIIA), but here you are
              distal end with V-Loc® suture (Covidien, MA, USA) transanally   mostly implementing either a double- or triple-stapling technique.
              or laparoscopically, so implementing a one-stapling technique
              (much reducing the cost) (Video 1). Otherwise, you may choose  conclusion
              to close the stump by a linear stapler, implementing a double-  Transanal NOSE is a feasible and flexible method that can minimize
              stapling technique.                              the complications associated with rectal and sigmoid resection. To
            •  B: Insert the anvil transanally, then choose.   our opinion, any surgeon experienced in colorectal laparoscopy can
              B1: If you are planning for an end-to-end anastomosis, then cut   easily apply this technique with a short learning curve.
              the proximal end, insert the anvil, then take a manual purse   supplementAry mAteriAls
                        1
              string suture,   or do a colotomyto insert the anvil through and
              use a linear stapler to close just around the anvil’s tip (author’s   Video 1: Closing the rectal stump after transanal NOSE after
              technique) (Video 2).                            low anterior resection using the direct exteriorization and

            © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.
            org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to
            the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain
            Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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