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Preoperative Scoring System to Predict Difficult LC
























            Fig. 13: Bar diagram showing association between preoperative grade   Fig. 15: ROC curve showing validity of preoperative score in predicting
            and intraoperative complications                   intraoperative complications

            Table 14: Validity of preoperative score in predicting intraoperative   Laparoscopic cholecystectomy is the gold standard treatment of
                                                                                                               20
            complications (total number of patients = 66)      choice for gallbladder disease (mainly symptomatic cholelithiasis).
                                                               Utmost caution has to be exercised while performing the procedure
             Area under the ROC curve (AUC)         0.900
                                                               as this treatment is not devoid of complications, albeit it is lower
                                                                                21
             Standard error                          0.0421    in experienced hands.  My study was aimed to develop a scoring
             95% confidence interval              0.802–0.960  method for difficult LC with a secondary objective of correlating
                                                               preoperative predictive factors with intraoperative difficulty in LC
             z-statistic                            9.508      by assessing the various preoperative predictors (history/clinical
             Significance level p (area = 0.5)     <0.0001     imaging). A study of 66 subjects to understand the preoperative
                                                               predictors of difficult LC revealed that the majority of them were
                                                               below or equal to 50 years of age (74.2%, n = 49), and most of
                                                               them were females (69.7%, n = 46). A majority of the patients were
                                                               obese, with 30 (45.5%) with a BMI >27.5 and 15 (22.7%) with a BMI
                                                                                    2
                                                               between 25 and 27.5 kg/m . In total, 41 out of 66 patients had
                                                               abdominal scars from previous operations, in which 31 (47%) had
                                                               an infraumbilical scar, and 10 (15.2%) had a supraumbilical scar. On
                                                               sonologic examination, 30 (45.5%) patients had a gallbladder wall
                                                               thickness of more than or equal to 4 mm, while 13 patients showed
                                                               pericholecystic collection and 14 patients had impacted stones.
                                                                  In our study, we developed a scoring system to preoperatively
                                                               ascertain the difficulty in LC based on clinical findings, history, and
                                                               sonology. The grades were categorized as easy (<5), difficult (5–10),
                                                               and very difficult (11–15). In total, 57 out of 66 cases were predicted
                                                               correctly by our scoring system (86.36%).
                                                                               22
                                                                  Randhawa et al.  in 2009 (88–92%, easy to difficult) and
                                                                          23
                                                               Dhanke et al.  in 2014 (94.05–100%, easy to difficult) published
                                                               similar findings.
                                                                  Higher BMI – 22 (73.3%) patients out of 30 with a BMI of >27.5
            Fig. 14: ROC curve showing validity of preoperative score in   kg/m  had difficult cholecystectomies. Gallbladder thickness >4
                                                                   2
            differentiating difficult and easy outcomes        mm also correctly predicted difficult cholecystectomies with
                                                               findings in 23 (76.6) patients, previous history of hospitalization
            Laparoscopic cholecystectomy was successfully performed on a   for cholecystitis also showed a positive correlation between it and
            human subject suffering from cholelithiasis by Philip Mouret in   difficulty in surgery with 11 (84.6) out of 13 patients having difficult
            1987 using an unmagnified mechanical rigid pipe without doing   cholecystectomies. Pericholecystic collection was the parameter
            laparotomy to remove the gallbladder.              with the highest association with difficulty in laparoscopy, 12
               The complication rate with LC was high initially but has now   (92.3%) out of 13 patients with collections underwent difficult
            reached a remarkably low level at 2.0–6.0% with an increase in   procedures. History of prior hospitalization, high BMI, and
                                                            18
            the expertise of the procedure and technological advancement.    pericholecystic collection are predictors of the difficulty of
                                                                                                             23
            A rate of 7–35% conversion to open cholecystectomy has been   laparoscopic cholecystectomy as described by Dhanke et al.  in
            reported in literature. 19                         2014 with whom our study is in agreement with. In 2005, Nachnani


                                                        World Journal of Laparoscopic Surgery, Volume 15 Issue 2 (May–August 2022)  137
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