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Gastric Remnant Perforation after Roux-en-Y Gastric Bypass
            recommendations. If there is an acute perforation with a small     2.   Iranmanesh P, Manisundaran NV, Bajwa KS, et al. Management of
            defect, the closure after biopsy is usually easy, performing a safe   acute gastric remnant complications after Roux-en-Y gastric bypass:
            and short laparoscopic procedure. Besides, it is recommendable   a single-center case series. Obes Surg 2020;30(7):2637–2641. DOI:
            to enable a gastric remnant access in the same surgery. It is also   10.1007/s11695-020-04537-w. Available from: https://pubmed.ncbi.
                                                                    nlm.nih.gov/32162207/.
            recommendable to perform a selective vagotomy to reduce the     3.   Iskandar ME, Chory FM, Goodman ER, et al. Diagnosis and management of
                        1
            acid production.  Gastric resection is sometimes executed in the   perforated duodenal ulcers following Roux-En-Y gastric bypass: a report
            second stage or when there is a large perforation or ischemia   of two cases and a review of the literature. Case Rep Surg 2015;2015:1–4.
                              2
            of the gastric remnant.  Resecting the excluded stomach may   DOI: 10.1155/2015/353468. Available from: https://pubmed.ncbi.nlm.nih.
            decrease the gastric acid production and avoid the formation of   gov/pmc/articles/PMC4408622/?report=abstract.
                           3
            gastrogastric fistula.  However, resecting the stomach implies short-    4.   Ovaere S, Tse WHW, Schipper EE, et al. Perforation of the
            term complications such as bleeding of omental vessels, necrosis   gastric remnant in a patient post-Roux-en-Y gastric bypass. BMJ
            of omental fat with abscess formation, or duodenal stump leakage.   Case Rep [Internet]. 2016;2016. DOI: 10.1136/bcr-2015-213862.
            Other complications such as bacterial overgrowth and vitamin B12   Available from: https://pubmed.ncbi.nlm.nih.gov/pmc/articles/
                                                                    PMC4785498/?report=abstract.
            deficiency have also been described. 3,10            5.   Dai L, Shah MM, Rosenblatt S. Perforated gastric remnant ulcer after
               Regarding discharge and follow-up, guidelines recommend   laparoscopic gastric bypass. BMJ Case Rep 2018;2018. DOI: 10.1136/
            H. pylori eradication when tests were positive, and recommend   bcr-2017-222190. Available from: https://pubmed.ncbi.nlm.nih.
            1-month treatment with PPI. 1,12                        gov/29622702/.
                                                                 6.   Bjorkman DJ, Alexander JR, Simons MA. Perforated duodenal ulcer
                                                                    after gastric bypass surgery. Am J Gastroenterol 1989;84(2):170–172.
            conclusion                                            7.   Tornese S, Aiolfi A, Bonitta G, et al. Remnant gastric cancer after
            Bariatric and general surgeons managing RYGBP patients should   Roux-en-Y gastric bypass: narrative review of the literature. Obes Surg
            not overlook gastric remnant complications in their differential   2019;29(8):2609–2613. DOI: 10.1007/s11695-019-03892-7. Available
            diagnosis of abdominal pain. Gastric remnant perforation should   from: https://pubmed.ncbi.nlm.nih.gov/31001760/.
            be taken into account if a bariatric patient presents with severe,     8.   Cleator LGM, Rae A, Birmingham CL, et al. Ulcerogenesis following
            epigastric abdominal pain without important radiological findings.   gastric procedures for obesity Obes Surg 1996;6(3):260–261.
            Risk factors are not clear, but H. pylori eradication is recommended.   DOI: 10.1381/096089296765556881. Available from: https://pubmed.
                                                                    ncbi.nlm.nih.gov/10729870/.
            Laparoscopic exploration should be performed urgently because     9.   Csendes A, Burgos AM, Smok G, et al. Endoscopic and histologic
            the operation time interval once the perforation has occurred is an   findings of the foregut in 426 patients with morbid obesity. Obes
            important predictor for morbidity and mortality. Defect closure or   Surg 2007;17(1):28–34. DOI: 10.1007/s11695-007-9002-9. Available
            gastric remnant resection may be performed without any general   from: https://pubmed.ncbi.nlm.nih.gov/17355765/.
            recommendations, but biopsies should be taken.       10.   Gypen BJ, Hubens GJA, Hartman V, et al. Perforated duodenal ulcer
                                                                    after laparoscopic gastric bypass. Obes Surg 2008;18(12):1644–1646.
                                                                    DOI: 10.1007/s11695-008-9530-y. Available from: https://pubmed.
            orcid                                                   ncbi.nlm.nih.gov/18443886/.
            Carlota Tuero   https://orcid.org/0000-0001-8577-5603    11.   Pohl D, Schmutz G, Plitzko G, et al. Perforated duodenal ulcers after
                                                                    Roux-Y Gastric Bypass. Am J Emerg Med 2018;36(8):1525.e1–1525.e3.
                                                                    DOI: 10.1016/j.ajem.2018.04.057. Available from: https://pubmed.
            references                                              ncbi.nlm.nih.gov/29716802/.
              1.   Plitzko G, Schmutz G, Kröll D, et al. Ulcer disease in the excluded     12.   Satoh K, Yoshino J, Akamatsu T, et al. Evidence-based clinical practice
                segments after Roux-en-Y gastric bypass: a current review of the   guidelines for peptic ulcer disease. J Gastroenterol 2016;51(3):177–194.
                literature. Obes Surg 2020;31(3):1280–1289. DOI: 10.1007/s11695-020-  DOI: 10.1007/s00535-016-1166-4. Available from: https://pubmed.
                05123-w.                                            ncbi.nlm.nih.gov/26879862/.






























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