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Gastric Cancer Resection
            upper endoscopy and biopsy. Surgical resectability was assessed   Afterward, we dissected the adipose tissue over the anterosuperior
            by multislice computed tomography abdomen (with IV and oral   border of the pancreas and LNs along the splenic vessels (station 11).
            contrast), where resectable tumors, according to TNM classification,   In locating proximal tumors, the proximal resection margin
            had to be T1-3, N0-1, and M0. All patients with infiltrating or   involved the whole proximal gastric segment with 2 to 3 cm
            metastatic cancer, peritoneal deposits, surgically unfit patient, or   esophageal safety margin using linear endo GIA stapler, 45 mm,
            pregnant women were excluded from the study. After the diagnosis   blue cartilage and a distal resection line of 5 cm safety margin.
            and assessment of eligibility, patients were randomized into two   In tumors occupying a large area of the stomach, total
            groups: group A had OG and group B had LG. Random assignment   gastrectomy was done with the duodenum transected 1 to 2 cm
            was done by the sealed envelope technique.         distal to the pylorus and the esophagus transected 2 to 3 cm
               All patients had signed an informed consent after a complete   proximal to the stomach.
            explanation of the risks and advantages of the surgery being   Reconstruction was done by Roux-en-Y jejunal anastomosis
            planned for them.                                  for total and distal resection and esophagogastric anastomosis in
               Baseline clinicopathological data were collected as age, sex,   upper radical resection.
            and tumor site.                                       A nasogastric tube inserted at the start of the operation was
                                                               then advanced to cross the anastomosis, just beforehand sewing
            Surgical Techniques                                the opening left after the side-to-side stapling. Finally, the resected
            Laparoscopic Gastrectomy                           specimens after putting in a retrieval bag were taken out through
            The patient was placed in supine position for the induction of   a 6-cm vertical supraumbilical incision that starts at the umbilicus.
                                                               The specimen was then checked for safety margins. A subphrenic
            general anesthesia with cuffed endotracheal tube and then placed   tubal drain was then inserted and left until the patient starts
            in French position. The operator stands between the legs of the   semisolid meals without evidence of anastomotic leaks or bleeding,
            patient. The cameraman stood on the patient’s right side, while   usually for 3 to 5 days.
            the first assistant stood on the patient’s left side and the tower is
            placed near the patient’s head.                    Open Gastrectomy
               A 10-mm camera port was created superior or inferior to the   A 10–15-cm incision length from the xiphisternum till below the
            umbilicus by open method, and pneumoperitoneum with carbon   umbilicus was used. Abdominal exploration was routinely done
            dioxide was induced to a pressure of up to 15 mm Hg.  to assess the tumor and exclude metastasis before proceeding to
               The peritoneal cavity was carefully checked for any secondaries.   the radical gastric resection. In general, we used the same steps as
            The table was turned into the steep reverse-Trendelenburg position,   in the laparoscopic resection.
            and four other trocars (one 12-mm and three 5-mm trocars) were
            placed carefully using laparoscopic vision. Thereafter, laparoscopic   Pre- and Postoperative Management
            D2 gastrectomy was performed as follows.           Pre- and postoperative management was the same for the two
               We start by dividing the gastrocolic ligament along its   groups. All patients received broad-spectrum antibiotics for
            transverse colon attachment using ultrasonic shears (Harmonic   48 hours during their postoperative hospitalization. Feeding was
            Scalpel TM; Ethicon Endo-Surgery Inc., Cincinnati, Ohio, United   started after passage of flatus. When the patients have adequate
            States). We started at the avascular plane to the left of the midline   pain control, tolerance of oral intake, ability to mobilize and self-
            and dissected toward the spleen till it reaches the left gastroepiploic   care, and no abnormal physical signs or laboratory test they were
            vessels that were divided. Division of the greater omentum was   discharged.
            continued in the direction of the first part of the duodenum, and   Perioperative data such as operative time, estimated
            the roots of the right gastroepiploic vessels were divided. The soft   intraoperative blood loss, intraoperative organ injury, postoperative
            tissues attached to the duodenum were dissected.   complications, histopathology of the tumor, and clinicopathological
               All LNs around the gastroepiploic vessels (stations 4d and 4sb)   TNM stage (according to the International Union Against Cancer
            were dissected followed by the infra-pyloric LNs (station 6), which   staging 10) were recorded. Postoperatively, 30-day follow-up data
            were dissected from the pylorus. At this stage, careful dissection   were collected to assess any complications, hospital stay duration,
            was usually done to avoid injury of gastrocolic trunk of Helen,   and need for ICU admission.
            which, if happened, will result in unnecessary bleeding. The lesser
            omentum was then entered at the pars flaccida, and the origin of   Data Management
            the right gastric artery was divided.              Data management including data entry and statistical analysis
               In the case of distally located tumors, the distal resection margin   were done by using IBM SPSS software, version 20. Quantitative
            was the duodenum 1 to 2 cm distal to the pylorus using a COVIDIEN   variables were presented in terms of mean ± SD, and qualitative
            Endo GIA Ultra Universal Stapler, 12 mm.           variables were expressed as frequency and percentage. Student’s
               The left gastric vein and artery were exposed by raising the   t-test and Chi-square test were used to compare the outcomes of
            stomach upward and to the right, completing dissection till the   two groups. The level of significance p-value was evaluated, where
            origin of the left gastric artery from the celiac trunks, where the   p-value <0.05 was considered statistically significant.
            artery was divided at its origin (station 7) using both clips and the
            ultrasonic shears. At this point, the LNs around the common hepatic
            artery were exposed and dissected. The perigastric LNs were   results
            dissected along the lesser curvature reaching the esophagogastric   During the study period, 73 patients were admitted to the
            junction. At least a proximal 5-cm resection margin starts from   department of general surgery at Assiut university hospital having
            the grossly malignant margin is done using COVIDIEN Endo GIA   GC and assessed for eligibility for possibility of curative resection.
            Ultra Universal Stapler, 12 mm (according to gastric wall thickness).   Twenty-seven patients were excluded as they were not meeting


                                                        World Journal of Laparoscopic Surgery, Volume 14 Issue 2 (May–August 2021)  107
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