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ORIGINAL ARTICLE
            A Randomized Clinical Trial of Laser Hemorrhoidoplasty vs

            Milligan and Morgan Hemorrhoidectomy


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            Hossein Shabahang , Ghodratollah Maddah , Ahmadali Mofidi , Mahdi Jabbari Nooghabi , Saeedeh Hajebi Khaniki 5
             AbstrAct
             Introduction: Hemorrhoidectomy is one of the most common surgical procedures, and other treatments such as laser hemorrhoidectomy
             had been used as an alternative. The aim of this study was to determine the outcome and postoperation complications of treatment by laser
             compared with open hemorrhoidectomy.
             Materials and methods: In this randomized clinical trial (RCT), 85 cases with a second or third degree of hemorrhoids were assigned to two
             groups at random and followed for 6 months. Those patients in the intervention group were treated by laser hemorrhoidoplasty (LHP) and
             those in the control group underwent Milligan and Morgan hemorrhoidectomy. At the end of follow-up, 80 cases remained in the trial on whom
             postoperative pain [visual analog scale (VAS)], complications, and quality of life according to the 36-item Short Form Health Survey (SF-36)
             questionnaire were studied. Data were analyzed using R 3.5.1 software and p value <0.05 was considered significant.
             Results: The most common complaints were bleeding (57%) and pain (41%). Postoperative pain immediately and after 6 months was not
             significantly different between the two groups (p > 0.05). No complications were seen in any groups in follow-up. All eight scales of SF-36
             questionnaire, except general health, were significantly different in the two groups. Physical functioning was lower in patients who underwent
             LHP, whereas the patients’ quality of life in other scales was better in the laser group. The total score of SF-36 was 66.1 ± 3.6 and 56.0 ± 3.3 in
             laser and surgery groups, respectively (p < 0.001).
             Conclusion: Laser hemorrhoidectomy is a safe procedure, not associated with any excessive postoperative complications. It improves patients’
             quality of life and can be a substitution of other surgical methods.
             Keywords: Complications, Hemorrhoidectomy, Laser, Quality of life.
             World Journal of Laparoscopic Surgery (2019): 10.5005/jp-journals-10033-1373

            IntroductIon                                       1–3 Endoscopic and Minimally Invasive Surgery Research Center,

            Hemorrhoid is one of the most common side effects of urbanization.   Mashhad University of Medical Sciences, Mashhad, Iran
            More than 50% of people are affected by this disease over the past   4 Department of Statistics, Ferdowsi University of Mashhad, Iran
            50 years, and the disease has been seen in both sexes and across   5 Student Research Committee, Department of Epidemiology and
            wide age ranges. As of today, signs of hemorrhoids are seen in 4.4%   Biostatistics, Mashhad University of Medical Sciences, Mashhad, Iran
            of the American population.                        Corresponding Author: Saeedeh Hajebi Khaniki,  Student Research
               Hemorrhoid is a familiar cause of admission to surgical clinics   Committee, Department of Epidemiology and Biostatistics, Mashhad
            and its treatment requires medical and surgical procedures, many of   University of Medical Sciences, Mashhad, Iran, Phone: +98 5138012806,
            which are performed for hemorrhoids of grades II, III, and IV. One of   e-mail: Hajebis951@mums.ac.ir
            the most prominent surgical procedures for hemorrhoids is Milligan   How to cite this article:  Shabahang  H,  Maddah  G,  Mofidi  A,  et al.
            and Morgan hemorrhoidectomy. Other techniques of hemorrhoid   A Randomized Clinical Trial of Laser Hemorrhoidoplasty vs Milligan
            surgery involve using devices such as stapler or procedures such   and Morgan Hemorrhoidectomy. World J Lap Surg 2019;12(2):59–63.
            as laser therapy. 1                                Source of support:  Mashhad University of Medical Sciences, Iran

               Using lasers was primarily recognized by Maymen in 1960 upon   Conflict of interest: None
            the construction of the ruby laser. In the following years, various
            types of lasers were designed and built, and with the discovery of   Using lasers in the treatment of hemorrhoid leads to minimal
            laser, a remarkable revolution was created in industrial, military,   tissue damage and good hemostasis, and it can also reduce the
            and medical world.                                 duration of surgery and hospital stay. However, against all the benefits,
               The laser was first used in medicine and ophthalmology.   specific training and precaution measurements are required to use
            Today, laser treatment is not uncommon in the treatment of   lasers in therapy. Moreover, to protect their eyes from invisible lights
            hemorrhoids for outpatients. During the treatment process,   produced by laser, it is a must that the surgeons use goggles. 2,3
            the arterial blood flow of hemorrhoids is halted using Doppler   In this study, the effects of two surgical methods of Milligan
            laser coagulation. In another method, laser is projected into the   and Morgan and the use of lasers in the treatment of hemorrhoids
            hemorrhoidal packet, causing subsequent fibrosis upon which   were evaluated in terms of the effectiveness of the treatment, the
            the hemorrhoidal packet shrinks and sticks to the anal canal wall   duration of surgery, and the possible complications caused by such
            to prevent its prolapse.                           medical methods.
               Various types of lasers are of great benefit in the field medicine.

            Their different wavelengths can exert different effects in the tissues.   MAterIAls And Methods
            The most popular lasers are the carbon dioxide laser, argon laser,   This study was a phase 3, randomized open blind trial. It consisted
            and neodymium: yttrium–aluminum garnet.            of two parallel groups. Eighty patients were studied between

            © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.
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