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Bariatric Surgery and Obesity
            1 patient (5.88%) (Fig. 1). Thepatients were kept on a follow-up for   ratio, which were noted preoperatively and at 4 weeks and 3 months
            3 months from the date of surgery. Particulars and demographic   postoperatively. The laboratory investigations included HbA1c and
            data of each patient were duly noted including their name, age,   lipid profile, e.g., serum triglycerides, serum cholesterol, serum HDL,
            sex, occupation, admission number, occupation, and address for   serum LDL, and serum VLDL.
            any future correspondence (Table 2).                  Patients presenting included in the study underwent
               The detailed history of each patient was obtained including   hematological, biochemical, and radiological investigations. For
            history of presenting symptoms, any preexisting comorbid   this, patients included in the study were informed regarding their
            conditions, and the patient’s past history including treatment and   inclusion, and a written informed consent was obtained from all
            surgical history.                                  the patients included in the study.
               General physical examination and a thorough systemic
            examination of all patients were carried out at the time of admission.  results
            All the necessary routine preliminary investigations were done. All   Effect on Anthropometric Parameters
            patients underwent specific anthropometric measurements such as   Weight was measured before surgery, at 4 weeks, and 3 months
            weight, BMI, waist circumference, hip circumference, and waist–hip
                                                               after surgery as depicted in Table 3. Preoperatively mean weight
                                                               was 138.71 ± 17.51 kg. Significant weight loss was observed at 4
                                                               weeks and 3 months when mean weight was 130.47 ± 14.77 kg and
                                                               116.53 ± 15.64 kg, respectively, thus concluding that the procedure
                                                               of bariatric surgery results in effective weight loss.
                                                                  Body mass index is calculated by weight (in kg) divided by
                                                                         2
                                                               height (in m ). The patient becomes eligible for bariatric surgery
                                                               depending upon this main parameter. There was a marked decrease
                                                               in BMI of the patients at 4 weeks and 3 months postoperatively that
                                                               was highly statistically significant.
                                                                  The waist circumference decreased from mean preoperative
                                                               132.94 cm to 126.47 cm at 4 weeks and to 106.93 cm at 3 months.
                                                               The mean hip circumference decreased from preoperative 124.50
                                                               cm to 119.14 cm at 4 weeks and 108.21 cm at 3 months. The waist:hip
                                                               ratio decreased from preoperative 1.06 cm to 1.05 cm at 4 weeks
                                                               and 0.98 cm at 3 months.

                                                               Effect on Biochemical Parameters
            Fig. 1: Distribution of patients on the basis of procedure done  There was a fall in HbA1c levels in patients (mean: 7.14 ± 2.62)
                                                               following bariatric surgery (Table 3). The fall in HbA1c levels at
            Table 2: Demographic data                          4 weeks (mean: 6.71 ± 2.22) and 3 months (mean: 5.57 ± 1.18)
            Number (n)                           17            postoperatively was significant in both the groups. Serum
            Mean age (years)                     43 ± 7.624    cholesterol levels showed a significant improvement (p = 0.003)
            Mean height (m)                      172.47 ± 6.09  at 4 weeks (mean: 209.47 ± 55.67 mg/dL) when compared with
                                                               preoperative levels (mean: 194.71 ± 47.17 mg/dL) and a highly
            Mean weight (kg)                     138.71 ± 17.51  significant improvement (p = 0.00) at 3 months (mean: 169.65 ±
                        2
            Mean BMI (kg/m )                     46.67 ± 6.230  31.06 mg/dL). Serum triglyceride levels showed an improvement
            Table 3: Value of various parameters before operation and after 4 weeks and 3 months of operation
                                                                                          Preoperative    Preoperative
                                     Preoperative         4 weeks          3 months        vs 4 weeks  vs 3 months
            Parameters           Mean     SD        Mean     SD       Mean     SD       p value       p value
            Weight (kg)          138.71   17.510    130.47   14.770   116.53   15.649   0.000        0.000
            Weight loss          –        –           8.47    3.68     22.29    4.91
            %EWL                 –        –          12.96    4.04     36.11    8.99
            Waist circumference  132.94   13.64     126.47   13.24    106.93   10.83    0.170        0.000
            Hip circumference    124.50    8.28     119.14    7.96    108.21    7.48    0.063        0.000
            Waist:hip ratio        1.06    0.06       1.05    0.06      0.98    0.05    0.630        0.002
            BMI                   46.67    6.230     43.95    5.317    38.67    4.610   0.000        0.000
            HbA1c                  7.14    2.628      6.71    2.222     5.57    1.181   0.008        0.002
            Serum cholesterol    209.47   55.679    194.71   47.170   169.65   31.068   0.003        0.000
            Triglyceride         305.47   76.81     287.70   70.87    250.88   63.08    0.488        0.030
            HDL                   25.23    5.70      29       5.91     38.94    8.16    0.067        0.0001
            LDL                   99.47   40.88      94.41   38.23     86      34.08    0.711        0.304
            VLDL                  37.23   15.91      35.82   14.79     32.47   11.87    0.790        0.330
            SD, standard deviation

             98   World Journal of Laparoscopic Surgery, Volume 12 Issue 3 (September–December 2019)
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