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Sugandha Agarwal
          diameter (< 6, 6–10, and >10 cm). The mean myoma diam-    3.  Palomba S, Zupi E, Falbo A, Russo T, Marconi D, Tolino A,
          eter was 4.99 ± 0.79 cm in the < 6 cm group, 7.33 ± 0.90 cm   Manguso F, Mattei A, Zullo F. A multicenter randomized,
          in the 6 to 10 cm group, and 11.66 ± 0.99 cm in the >10 cm   controlled study comparing laparoscopic versus minilapa-
          group. There were no statistically significant differences   rotomic myomectomy: reproductive outcomes. Fertil Steril
                                                                  2007 Oct;88(4):933-941.
          across the three groups in total operation time. However,     4.  Bush AJ, Morris SN, Millham FH, Isaacson KB. Women’s pref-
          the expected blood loss was lowest in the <6 cm group   erences for minimally invasive incisions. J Minim Invasive
          (132.80 ± 122.32 mL) compared with the other two groups   Gynecol 2011 Sep-Oct;18(5):640-643.
          (210.97 ± 157.72 mL in the 6 to 10 cm group and 256.00 ±     5.  Goebel K, Goldberg JM. Women’s preference of cosmetic
          215.48 mL in the >10 cm group), representing a statisti-  results after gynecologic surgery. J Minim Invasive Gynecol
                                                                  2014 Jan-Feb;21(1):64-67.
          cally significant trend (p = 0.078).                  6.  FDA Safety Communication. Updated laparoscopic uterine
             It is important to note that robotic myomectomy is   power morcellation in hysterectomy  and myomectomy.
          a significantly lengthier procedure compared with con-  2014. Available from: http://www.fda.gov/MedicalDevices/
                                           13
          ventional laparoscopic myomectomy,  but the robotic     Safety/AlertsandNotices/ucm424443.htm.
          platform allows for a broader range of applications com-    7.  Han CM, Lee CL, Su H, Wu PJ, Wang CJ, Yen CF. Single-
          pared with conventional laparoscopy for this indication.   port laparoscopic myomectomy: initial operative experi-
                                                                  ence and comparative outcome. Arch Gynecol Obstet 2013
          Also, the obese can realize the same clinical and quality   Feb;287(2):295-300.
          benefits of minimally invasive surgery as the nonobese     8.  Choi CH, Kim TH, Kim SH, Choi JK, Park JY, Yoon A, Lee YY,
          at the cost of additional operative time.               Kim TJ, Lee JW, Kim BG, et al. Surgical outcomes of a new
             One of the aims of this study was to analyze the     approach to laparoscopic myomectomy: single-port and
          comprehensive cost of this procedure. However, none of   modified suture technique. J Minim Invasive Gynecol 2014
                                                                  Jul-Aug;21(4):580-585.
          the studies reported on the cost analysis. Only one study     9.  Yoshiki N, Okawa T, Kubota T. Single-incision laparoscopic
          compared the robotic modality with its laparoscopic     myomectomy with intracorporeal suturing. Fertil Steril 2011
          counterpart and found an associated higher cost with the   Jun;95(7):2426-2428.
                          18
          robotic technique.  This is an important area that needs     10.  Bendient CE, Magrina JF, Noble BN, Kho RM. Comparison of
          to be further studied, especially, to understand if a wider   robotic and laparoscopic myomectomy. Am J Obstet Gynecol
          application of this technique is economically feasible.   2009 Dec;201(6):566.e1-566.e5.
          Another limitation is that in all the studies, the surgeries     11.  Nezhat C, Lavie O, Hsu S, Watson J, Barnett O, Lemyre M.
                                                                  Robotic-assisted laparoscopic myomectomy compared
          were performed by highly experienced surgeons in the    with standard laparoscopic myomectomy—a retrospec-
          field of minimally invasive and robot-assisted surgery,   tive matched control study. Fertil Steril 2009 Feb;91(2):
          and it is, therefore, unclear whether these techniques   556-559.
          would translate to successful adoption by the larger     12.  Advincula AP, Xu X, Goudeau S 4th, Ransom SB. Robot-
          surgical community.                                     assisted laparoscopic myomectomy versus abdominal
                                                                  myomectomy: a comparison of short-term surgical outcomes
                                                                  and immediate costs. J Minim Invasive Gynecol 2007 Nov-
          CONCLUSION                                              Dec;14(6):698-705.
                                                                13.  Gargiulo AR, Srouji SS, Missmer SA, Correia KF, Vellinga TT,
          Current initial data indicate that RA-LESS is a promis-  Einarsson JI. Robot-assisted laparoscopic myomectomy
          ing technique. It is a safe, feasible, and reproducible   compared with standard laparoscopic myomectomy. Obstet
          procedure for performing myomectomy. However, more      Gynecol 2012 Aug;120(2 Pt 1):284-291.
          studies with larger cohorts and long-term follow-ups are     14.  Eisenberg D, Vidovszky TJ, Lau J, Guiroy B, Rivas H. Com-
          needed to conclusively recommend this technique for a   parison of robotic and laparoendoscopic single-site surgery
          wider application. Also, the exact indications for its use   systems in a suturing and knot tying task. Surg Endosc 2013
                                                                  Sep;27(9):3182-3186.
          and patient selection criteria for optimum outcome still     15.  Lewis EI, Srouji SS, Gargiulo AR. Robotic single site myo-
          need to be determined.                                  mectomy: initial report and technique. Fertil Steril 2015
                                                                  May;103(5):1370-1377.
          REFERENCES                                            16.  Gargiulo AR, Lewis EI, Kaser DJ, Srouji SS. Robotic single
                                                                  site myomectomy: a step by step tutorial. Fertil Steril 2015
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              Laparoscopic versus abdominal myomectomy: a prospective,     17.  Choi EJ, Rho AM, Lee SR, Jeong K, Moon HS. Robotic single-
              randomized trial to evaluate benefits in early outcome. Am J   site myomectomy: clinical analysis of 61 consecutive cases. J
              Obstet Gynecol 1996 Feb;174(2):654-658.             Minim Invasive Gynecol 2017 May-Jun;24(4):632-639.
            2.  Seracchioli R, Rossi S, Govoni F, Rossi E, Venturoli S, Bul-    18.  Gargiulo AR, Choussein S, Srouji SS, Cedo LE, Escobar PF.
              letti C, Flamigni C. Fertility and obstetric outcome after   Coaxial robot assisted laparoendoscopic single site myomec-
              laparoscopic myomectomy of large myomata: a randomized   tomy. J Robotic Surg 2017 Mar;11(1):27-35.
              comparison with abdominal myomectomy. Hum Reprod 2000     19.  Sendag F, Akdemir A, Oztekin MK. Robotic single-incision
              Dec;15(12):2663-2668.                               transumbilical total hysterectomy using a single-site robotic
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