Page 8 - World Journal of Laparoscopic Surgeons
P. 8

Hesham Kasem, Wael Alshahat
          lavage was done and closed suction drain was inserted     Table 2: Operative time and postoperative course
          in the pelvis.                                      Variable            LA         OA          p-value
             Open appendectomy has been done through right    Operative time (min)  59.6 ± 20.3  62.8 ± 28.6 >0.05 NS
          lower quadrant incision with muscle cutting when    Length of hospital stay   3.5 ± 2.6  5.8 ± 2.9  >0.05 NS
          required. Postoperatively, intravenous ceftriaxone 50   (days)
          to 100 mg/kg once daily, and metronidazole 10 mg/   NS: Nonsignificant
          kg/8 hr were given until fever subsided and the white         Table 3: Postoperative complications
          blood cells count decreased, and the patients were dis-  Variable            LA      OA         p-value
          charged when they can tolerate feeding and no fever and   Wound infection    2 (4.5%) 3 (8.1%)  <0.05
          continued on oral antibiotic cefixime 7 mg once daily   Abdominal infection  0       2 (5.4%)  <0.05
          and metronidazol oral 10 mg/kg/8 hr for 1 week. All   Adhesive intestinal obstruction  0  1 (2.7%)  <0.05
          appendices were sent for histopathology. Pus was sent   Readmission          0       2 (5.4%)  <0.05
          for culture and drug sensitivity. They were followed up   Total              2 (4.5%) 8 (21.6%) <0.05
          in the outpatient clinic 5 days after their discharge from
          the hospital. Perforated appendicitis has been diagnosed   8.1.5%; p < 0.05). The occurrence of the intraabdominal
          by the presence of pus either localized or generalized or   abscess was significantly lower in the LA group (0 vs
          the presence of visible perforation or fecalith operative   5.4%; p < 0.05).
          time was calculated from the end of the anesthesia till
          the end of the suturing.                            DISCUSSION

          RESULTS                                             Open appendectomy has been done through muscle
                                                              splitting right lower quadrant incision since long time,
          Eighty-one children who underwent appendectomy      but recently, LA appendectomy has been increasing, and
          for perforated appendicitis between January 2013 and   some surgeons perform it routinely, others select cases,
          October 2016 were included in the study among 81    and some others still do it open.  The advantages of LA
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          patients of whom 53 were male and 28 were female; 44   include short hospital stay, less postoperative pain, good
          children underwent LA and 37 had OA. The demographic   exploration of the abdomen, fewer complications, but
          characteristics are shown in Table 1. The majority of   its routine use in complicated appendicitis is still con-
          the patients were male. This difference was statistically   troversial.  The operative time depends on the surgical
                                                                      1
          significant (p < 0.05). There was no difference between   skills and the degree of inflammation of the appendix.
          LA and OA groups with respect to mean age (p > 0.05).   Although LA surgery takes time for preparation, and
          The median operative time in the LA group was 51.6 ±   connection of the tubes and also working in a small
          20.3 minutes, compared with the OA group (62.8 ± 28.6   space provide some difficulties and require meticulous
          minutes). There was no difference (p > 0.05). There was no   introduction of the instruments, OA also takes time
          conversion to open in the LA group. The histopathology   for opening and closure of the abdomen, especially in
          in the OA group was acute suppurative appendicitis in   obese patients and if muscle cutting was done. In our
          29 patients and gangrenous appendicitis in 15 patients,   study, we did not observe any difference in the operative
          and in the LA, in 25 patients, it was acute suppurative   time between open and LA group; this is mainly due to
          appendicitis and in 12 patients, it was gangrenous appen-  increased surgical experience in LA surgery. Also in a
          dicitis. A significant difference was found as regards the   study done by Li et al,  there was no difference in the
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          duration of hospitalization between OA and LA; it was 3.5   operative time.  Some studies also reported no differ-
                                                                           10
          ± 2.6 vs 5.8 ± 2.9 days (p < 0.05). We had 7 children (13.6%)   ence in the operative time. 4,6,11  And some other studies
          who developed postoperative complications in the LA   reported increased operative time for LA compared
          group and 17 patients (45.9%) in the OA group (Tables 2    with OA in perforated appendicitis.  During LA, intra-
                                                                                             7-9
          and 3) with significant difference, p < 0.05. Children in   operative complications can occur as visceral injury or
          the LA group had a lower rate of wound infection (4.5 vs.
                                                              parietal bleeding during trocar insertion. In one study,
                                                              the incidence of bowel injury during LA was reported
                      Table 1: Patient’s demographics
                                                              to be 0.8% and this injury can occur due to dissecting of
           Variable         LA          OA            p-value  the inflamed friable bowel or dissecting at the base of the
           Number           44          37            NS      appendix. In our study, we did not encounter any bowel
           Age              7.6 (3–14)  8.2 (5–14)    NS           10
           Sex (male:female)  30:14     23:14       <0.05     injury.  Bleeding also can occur during LA which is due
                            (68.1:31.8%)  (62.1:37.8%)        to improper control of mesoappendix. The reported inci-
           NS: Nonsignificant                                 dence of bleeding from mesoappendix in LA in a large
          2
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