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Peptic Ulcer

Discussion in 'All Categories' started by Sridhar - Jun 28th, 2024 3:35 pm.
Sridhar	I am suffering from Peptic Ulcer. What are the available treatment options for peptic ulcers? What medications will I need to take, and what are their potential side effects?
re: Peptic Ulcer by Dr. B. S. Bhalla - Jun 28th, 2024 3:41 pm #1
Dr. B. S. Bhalla	Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine. They are usually caused by Helicobacter pylori (H. pylori) infection or the use of nonsteroidal anti-inflammatory drugs (NSAIDs). The treatment options for peptic ulcers focus on reducing the acid levels in the stomach, eradicating H. pylori infection if present, and protecting the lining of the stomach and intestines. Treatment Options for Peptic Ulcers Medications to Reduce Stomach Acid Proton Pump Inhibitors (PPIs): These reduce stomach acid by blocking the enzyme in the stomach wall that produces acid. Examples: Omeprazole, Lansoprazole, Esomeprazole, Pantoprazole, Rabeprazole. Side Effects: Headache, diarrhea, constipation, abdominal pain, nausea, and increased risk of bone fractures with long-term use. H2-Receptor Antagonists: These reduce the amount of acid released into your digestive tract. Examples: Ranitidine, Famotidine, Cimetidine, Nizatidine. Side Effects: Headache, dizziness, constipation, diarrhea, and fatigue. Antibiotics to Eradicate H. pylori These are used if your ulcer is caused by H. pylori infection. Typically, a combination of antibiotics is prescribed. Examples: Amoxicillin, Clarithromycin, Metronidazole, Tetracycline. Side Effects: Nausea, vomiting, diarrhea, metallic taste in the mouth, and allergic reactions in some people. Medications to Protect the Stomach Lining Cytoprotective Agents: These help protect the tissues that line your stomach and small intestine. Examples: Sucralfate, Misoprostol. Side Effects: Sucralfate can cause constipation. Misoprostol can cause diarrhea, abdominal pain, and uterine contractions (not suitable for pregnant women). Antacids These neutralize existing stomach acid and can provide rapid pain relief. Examples: Aluminum hydroxide, Magnesium hydroxide, Calcium carbonate. Side Effects: Constipation (aluminum-based antacids), diarrhea (magnesium-based antacids), and potential kidney problems with prolonged use. Lifestyle and Home Remedies Avoid NSAIDs: If NSAIDs are the cause, your doctor might recommend discontinuing their use. Dietary Changes: Avoid spicy foods, alcohol, and caffeine. Eat smaller, more frequent meals. Quit Smoking: Smoking increases stomach acid and impairs healing. Manage Stress: Stress can exacerbate symptoms. Follow-Up Care Regular follow-up visits with your healthcare provider are essential to ensure that the treatment is effective and to monitor for any potential complications.