itp remooval of spleen
| Discussion in 'All Categories' started by sulfi - Feb 12th, 2013 12:34 am. | |
sulfi
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This is for my brother he have problem with ITP he meet diffrent hospital they said after the surgerey the disese will not compleatly solve and if we do without surgery we need to eat long time tablets..please give the advice for this disease and please let me know in india for this disease best treatment hospital..thanks alot Regarsds sulfi |
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re: itp remooval of spleen
by Dr J S Chowhan -
Feb 21st, 2013
2:11 pm
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Dr J S Chowhan
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Dear Sulfi Adult chronic immune thrombocytopenic purpura (ITP) can be an autoimmune disorder manifested by thrombocytopenia from the results of antiplatelet autoantibodies and T lymphocyte-mediated platelet cytotoxicity. Multiple studies show that corticosteroid treatment and splenectomy, alone or together, increase platelet counts to safe levels in 60% to 70% of patients. However, there is little change facts about the outcome of ITP patients refractory to splenectomy. To sum up, approximately 75% of patients with RefITP eventually achieved remission, though remission occurred slowly. Patients who did not achieve remission instead experienced a very difficult disease course with significant morbidity and mortality. It will be possible that newer forms of treatment, including rituximab, thrombopoietic factors, and monoclonal antibodies affecting key pathways from the immune system, may alter outcomes because of this extremely resistant subgroup. New therapeutic approaches are incredibly needed. With regards J S Chowhan |